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ORBIMED ADVISORS LLC
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| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | STRYKER CORP | SYK | 271,400 | -96,200 | 82,801,426,000 | -22,137,346,000 | $305,090.00 |
| 03/31/2023 | STRYKER CORP | SYK | 367,600 | -113,400 | 104,938,772,000 | -12,660,918,000 | $285,470.00 |
| 12/31/2022 | STRYKER CORP | SYK | 481,000 | 57,900 | 117,599,690,000 | 117,513,995,000 | $244,490.00 |
| 09/30/2022 | STRYKER CORP | SYK | 423,100 | -18,000 | 85,695,000 | -2,053,000 | $202.54 |
| 06/30/2022 | STRYKER CORP | SYK | 441,100 | -16,000 | 87,748,000 | -34,458,000 | $198.93 |
| 03/31/2022 | STRYKER CORP | SYK | 457,100 | -8,200 | 122,206,000 | -2,225,000 | $267.35 |
| 12/31/2021 | STRYKER CORP | SYK | 465,300 | 127,900 | 124,431,000 | 36,798,000 | $267.42 |
| 06/30/2021 | STRYKER CORP | SYK | 337,400 | 0 | 87,633,000 | 5,449,000 | $259.73 |
| 03/31/2021 | STRYKER CORP | SYK | 337,400 | 102,400 | 82,184,000 | 24,600,000 | $243.58 |
| 12/31/2020 | STRYKER CORP | SYK | 235,000 | 0 | 57,584,000 | 8,617,000 | $245.04 |
| 09/30/2020 | STRYKER CORP | SYK | 235,000 | 235,000 | 48,967,000 | 48,967,000 | $208.37 |
| 06/30/2020 | STRYKER CORP | SYK | 0 | -371,100 | 0 | -61,784,000 | |
| 03/31/2020 | STRYKER CORP | SYK | 371,100 | 371,100 | 61,784,000 | 61,784,000 | $166.49 |
| 09/30/2019 | STRYKER CORP | SYK | 0 | -54,000 | 0 | -11,101,000 | |
| 06/30/2019 | STRYKER CORP | SYK | 54,000 | 0 | 11,101,000 | 435,000 | $205.57 |
| 03/31/2019 | STRYKER CORP | SYK | 54,000 | -76,200 | 10,666,000 | -9,743,000 | $197.52 |
| 12/31/2018 | STRYKER CORP | SYK | 130,200 | 0 | 20,409,000 | -2,725,000 | $156.75 |
| 09/30/2018 | STRYKER CORP | SYK | 130,200 | -13,200 | 23,134,000 | -1,081,000 | $177.68 |
| 06/30/2018 | STRYKER CORP | SYK | 143,400 | -92,900 | 24,215,000 | -13,810,000 | $168.86 |
| 03/31/2018 | STRYKER CORP | SYK | 236,300 | -49,700 | 38,025,000 | -6,259,000 | $160.92 |
| 12/31/2017 | STRYKER CORP | SYK | 286,000 | -135,000 | 44,284,000 | -15,506,000 | $154.84 |
| 09/30/2017 | STRYKER CORP | SYK | 421,000 | 104,700 | 59,790,000 | 15,894,000 | $142.02 |
| 06/30/2017 | STRYKER CORP | SYK | 316,300 | 0 | 43,896,000 | 2,255,000 | $138.78 |
| 03/31/2017 | STRYKER CORP | SYK | 316,300 | 0 | 41,641,000 | 3,745,000 | $131.65 |
| 12/31/2016 | STRYKER CORP | SYK | 316,300 | 104,300 | 37,896,000 | 13,217,000 | $119.81 |
| 09/30/2016 | STRYKER CORP | SYK | 212,000 | 0 | 24,679,000 | -725,000 | $116.41 |
| 06/30/2016 | STRYKER CORP | SYK | 212,000 | 212,000 | 25,404,000 | 25,404,000 | $119.83 |
| 03/31/2016 | STRYKER CORP | SYK | 212,000 | 26,000 | 22,745,000 | 5,458,000 | $107.29 |
| 12/31/2015 | STRYKER CORP | SYK | 186,000 | 71,200 | 17,287,000 | 10,994,000 | $92.94 |
| 09/30/2015 | STRYKER CORP | SYK | 186,000 | 71,200 | 17,503,000 | 11,210,000 | $94.10 |
| 06/30/2015 | STRYKER CORP | SYK | 0 | -114,800 | 0 | -6,293,000 | |
| 03/31/2015 | STRYKER CORP | SYK | 1,113,000 | 998,200 | 102,674,000 | 96,381,000 | $92.25 |
| 12/31/2014 | STRYKER CORP | SYK | 1,031,600 | 916,800 | 97,311,000 | 91,018,000 | $94.33 |
| 09/30/2014 | STRYKER CORP | SYK | 1,002,600 | 887,800 | 80,960,000 | 74,667,000 | $80.75 |
| 06/30/2014 | STRYKER CORP | SYK | 994,600 | 879,800 | 83,865,000 | 77,572,000 | $84.32 |
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