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ORBIMED ADVISORS LLC
> XFOR
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | X4 Pharmaceuticals, Inc | XFOR | 7,133,515 | 1,315,789 | 13,839,019,000 | 8,777,597,000 | $1,940.00 |
| 03/31/2023 | X4 Pharmaceuticals, Inc | XFOR | 5,817,726 | 0 | 5,061,422,000 | -715,580,000 | $870.00 |
| 12/31/2022 | X4 Pharmaceuticals, Inc | XFOR | 5,817,726 | 790,909 | 5,777,002,000 | 5,768,406,000 | $993.00 |
| 09/30/2022 | X4 Pharmaceuticals, Inc | XFOR | 5,026,817 | 3,652,968 | 8,596,000 | 7,270,000 | $1.71 |
| 06/30/2022 | X4 Pharmaceuticals, Inc | XFOR | 1,373,849 | 0 | 1,326,000 | -1,078,000 | $0.97 |
| 03/31/2022 | X4 Pharmaceuticals, Inc | XFOR | 1,373,849 | 0 | 2,404,000 | -742,000 | $1.75 |
| 12/31/2021 | X4 Pharmaceuticals, Inc | XFOR | 1,373,849 | 0 | 3,146,000 | -5,784,000 | $2.29 |
| 06/30/2021 | X4 Pharmaceuticals, Inc | XFOR | 1,373,849 | 0 | 8,930,000 | -2,899,000 | $6.50 |
| 03/31/2021 | X4 Pharmaceuticals, Inc | XFOR | 1,373,849 | 287,356 | 11,829,000 | 4,843,000 | $8.61 |
| 03/23/2021 | X4 Pharmaceuticals, Inc | XFOR | 1,835,993 | 749,500 | 17,093,095 | 10,107,095 | $9.31 |
| 12/31/2020 | X4 Pharmaceuticals, Inc | XFOR | 1,086,493 | 0 | 6,986,000 | -370,000 | $6.43 |
| 09/30/2020 | X4 Pharmaceuticals, Inc | XFOR | 1,086,493 | 0 | 7,356,000 | -2,770,000 | $6.77 |
| 06/30/2020 | X4 Pharmaceuticals, Inc | XFOR | 1,086,493 | 0 | 10,126,000 | -739,000 | $9.32 |
| 03/31/2020 | X4 Pharmaceuticals, Inc | XFOR | 1,086,493 | 0 | 10,865,000 | -760,000 | $10.00 |
| 12/31/2019 | X4 Pharmaceuticals, Inc | XFOR | 1,086,493 | 150,000 | 11,625,000 | -278,000 | $10.70 |
| 09/30/2019 | X4 Pharmaceuticals, Inc | XFOR | 936,493 | 0 | 11,903,000 | -2,144,000 | $12.71 |
| 06/30/2019 | X4 Pharmaceuticals, Inc | XFOR | 936,493 | 625,000 | 14,047,000 | 8,624,000 | $15.00 |
| 04/16/2019 | X4 Pharmaceuticals, Inc | XFOR | 1,248,993 | 937,500 | 18,197,828 | 17,229,085 | $14.57 |
| 03/31/2019 | X4 Pharmaceuticals, Inc | XFOR | 311,493 | 0 | 5,423,000 | 4,454,257 | $17.41 |
| 03/13/2019 | X4 Pharmaceuticals, Inc | XFOR | 311,493 | 311,493 | 968,743 | 968,743 | $3.11 |
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