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BAKER BROS. ADVISORS LP
> BGNE
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | BeiGene, Ltd. | BGNE | 11,668,897 | 0 | 2,080,564,335,000 | -485,892,871,000 | $178,300.00 |
| 12/31/2022 | BeiGene, Ltd. | BGNE | 11,668,897 | 0 | 2,566,457,206,000 | 2,564,884,005,000 | $219,940.00 |
| 09/30/2022 | BeiGene, Ltd. | BGNE | 11,668,897 | 0 | 1,573,201,000 | -315,410,000 | $134.82 |
| 06/30/2022 | BeiGene, Ltd. | BGNE | 11,668,897 | 0 | 1,888,611,000 | -312,143,000 | $161.85 |
| 03/31/2022 | BeiGene, Ltd. | BGNE | 11,668,897 | 0 | 2,200,754,000 | -960,700,000 | $188.60 |
| 12/31/2021 | BeiGene, Ltd. | BGNE | 11,668,897 | 0 | 3,161,454,000 | -1,074,356,000 | $270.93 |
| 09/30/2021 | BeiGene, Ltd. | BGNE | 11,668,897 | 0 | 4,235,810,000 | 231,161,000 | $363.00 |
| 06/30/2021 | BeiGene, Ltd. | BGNE | 11,668,897 | 0 | 4,004,649,000 | -57,061,000 | $343.19 |
| 03/31/2021 | BeiGene, Ltd. | BGNE | 11,668,897 | 0 | 4,061,710,000 | 1,046,584,000 | $348.08 |
| 12/31/2020 | BeiGene, Ltd. | BGNE | 11,668,897 | -1,632,700 | 3,015,126,000 | -794,983,000 | $258.39 |
| 09/30/2020 | BeiGene, Ltd. | BGNE | 13,301,597 | 1,524,312 | 3,810,109,000 | 1,591,269,000 | $286.44 |
| 07/12/2020 | BeiGene, Ltd. | BGNE | 173,965,588 | 162,188,303 | 34,102,474,216 | 31,883,634,216 | $196.03 |
| 06/30/2020 | BeiGene, Ltd. | BGNE | 11,777,285 | 0 | 2,218,840,000 | 768,938,000 | $188.40 |
| 03/31/2020 | BeiGene, Ltd. | BGNE | 11,777,285 | 0 | 1,449,902,000 | -502,301,000 | $123.11 |
| 12/31/2019 | BeiGene, Ltd. | BGNE | 11,777,285 | 0 | 1,952,203,000 | 509,957,000 | $165.76 |
| 09/30/2019 | BeiGene, Ltd. | BGNE | 11,777,285 | 0 | 1,442,246,000 | -17,548,000 | $122.46 |
| 06/30/2019 | BeiGene, Ltd. | BGNE | 11,777,285 | -182,539 | 1,459,794,000 | -118,903,000 | $123.95 |
| 03/31/2019 | BeiGene, Ltd. | BGNE | 11,959,824 | 0 | 1,578,697,000 | -98,788,000 | $132.00 |
| 12/31/2018 | BeiGene, Ltd. | BGNE | 11,959,824 | 0 | 1,677,485,000 | -382,236,000 | $140.26 |
| 09/30/2018 | BeiGene, Ltd. | BGNE | 11,959,824 | 0 | 2,059,721,000 | 221,137,000 | $172.22 |
| 07/26/2018 | BeiGene, Ltd. | BGNE | 155,703,388 | 151,854,157 | 26,955,370,531 | 26,579,223,531 | $173.12 |
| 06/30/2018 | BeiGene, Ltd. | BGNE | 11,959,824 | 8,110,593 | 1,838,584,000 | 1,462,437,000 | $153.73 |
| 01/17/2018 | BeiGene, Ltd. | BGNE | 155,484,836 | 151,586,405 | 15,957,408,719 | 15,554,076,719 | $102.63 |
| 12/31/2017 | BeiGene, Ltd. | BGNE | 3,849,231 | -49,200 | 376,147,000 | -27,185,000 | $97.72 |
| 09/30/2017 | BeiGene, Ltd. | BGNE | 3,898,431 | 225,256 | 403,332,000 | 238,039,000 | $103.46 |
| 08/10/2017 | BeiGene, Ltd. | BGNE | 130,374,760 | 126,701,585 | 9,507,579,373 | 9,342,286,373 | $72.93 |
| 06/30/2017 | BeiGene, Ltd. | BGNE | 3,673,175 | 0 | 165,293,000 | 30,818,000 | $45.00 |
| 03/31/2017 | BeiGene, Ltd. | BGNE | 3,673,175 | 0 | 134,475,000 | 22,957,000 | $36.61 |
| 12/31/2016 | BeiGene, Ltd. | BGNE | 3,673,175 | 1,760,495 | 111,518,000 | 52,588,000 | $30.36 |
| 09/30/2016 | BeiGene, Ltd. | BGNE | 1,912,680 | 0 | 58,930,000 | 1,932,000 | $30.81 |
| 06/30/2016 | BeiGene, Ltd. | BGNE | 1,912,680 | 0 | 56,998,000 | 937,000 | $29.80 |
| 03/31/2016 | BeiGene, Ltd. | BGNE | 1,912,680 | 1,912,680 | 56,061,000 | 56,061,000 | $29.31 |
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