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BAKER BROS. ADVISORS LP
> AFMD
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Affimed N.V. | AFMD | 6,596,830 | 0 | 3,946,224,000 | -4,233,845,000 | $598.20 |
| 12/31/2022 | Affimed N.V. | AFMD | 6,596,830 | 0 | 8,180,069,000 | 8,166,480,000 | $1,240.00 |
| 09/30/2022 | Affimed N.V. | AFMD | 6,596,830 | 0 | 13,589,000 | -4,684,000 | $2.06 |
| 06/30/2022 | Affimed N.V. | AFMD | 6,596,830 | 1,443,661 | 18,273,000 | -4,246,000 | $2.77 |
| 03/31/2022 | Affimed N.V. | AFMD | 5,153,169 | 2,500,000 | 22,519,000 | 7,874,000 | $4.37 |
| 12/31/2021 | Affimed N.V. | AFMD | 2,653,169 | 2,488,564 | 14,645,000 | 13,628,000 | $5.52 |
| 09/30/2021 | Affimed N.V. | AFMD | 164,605 | 0 | 1,017,000 | -382,000 | $6.18 |
| 06/30/2021 | Affimed N.V. | AFMD | 164,605 | 0 | 1,399,000 | 97,000 | $8.50 |
| 03/31/2021 | Affimed N.V. | AFMD | 164,605 | 0 | 1,302,000 | 344,000 | $7.91 |
| 12/31/2020 | Affimed N.V. | AFMD | 164,605 | -25,195 | 958,000 | 315,000 | $5.82 |
| 09/30/2020 | Affimed N.V. | AFMD | 189,800 | -10,200 | 643,000 | -280,000 | $3.39 |
| 06/30/2020 | Affimed N.V. | AFMD | 200,000 | 0 | 923,000 | 607,000 | $4.62 |
| 03/31/2020 | Affimed N.V. | AFMD | 200,000 | 0 | 316,000 | -232,000 | $1.58 |
| 12/31/2019 | Affimed N.V. | AFMD | 200,000 | 0 | 548,000 | -40,000 | $2.74 |
| 09/30/2019 | Affimed N.V. | AFMD | 200,000 | 0 | 588,000 | 14,000 | $2.94 |
| 06/30/2019 | Affimed N.V. | AFMD | 200,000 | 0 | 574,000 | -266,000 | $2.87 |
| 03/31/2019 | Affimed N.V. | AFMD | 200,000 | 0 | 840,000 | 218,000 | $4.20 |
| 12/31/2018 | Affimed N.V. | AFMD | 200,000 | 0 | 622,000 | -248,000 | $3.11 |
| 09/30/2018 | Affimed N.V. | AFMD | 200,000 | -200,000 | 870,000 | 210,000 | $4.35 |
| 06/30/2018 | Affimed N.V. | AFMD | 400,000 | 0 | 660,000 | 140,000 | $1.65 |
| 12/31/2017 | Affimed N.V. | AFMD | 400,000 | 0 | 520,000 | -380,000 | $1.30 |
| 09/30/2017 | Affimed N.V. | AFMD | 400,000 | 0 | 900,000 | 80,000 | $2.25 |
| 06/30/2017 | Affimed N.V. | AFMD | 400,000 | 0 | 820,000 | -100,000 | $2.05 |
| 03/31/2017 | Affimed N.V. | AFMD | 400,000 | 0 | 920,000 | 200,000 | $2.30 |
| 12/31/2016 | Affimed N.V. | AFMD | 400,000 | 0 | 720,000 | -392,000 | $1.80 |
| 09/30/2016 | Affimed N.V. | AFMD | 400,000 | 0 | 1,112,000 | 120,000 | $2.78 |
| 06/30/2016 | Affimed N.V. | AFMD | 400,000 | 0 | 992,000 | -504,000 | $2.48 |
| 03/31/2016 | Affimed N.V. | AFMD | 400,000 | 0 | 1,496,000 | -1,352,000 | $3.74 |
| 12/31/2015 | Affimed N.V. | AFMD | 400,000 | 400,000 | 2,848,000 | 2,848,000 | $7.12 |
| 09/30/2015 | Affimed N.V. | AFMD | 400,000 | 400,000 | 2,468,000 | 2,468,000 | $6.17 |
| 06/30/2015 | Affimed N.V. | AFMD | 400,000 | 400,000 | 5,388,000 | 5,388,000 | $13.47 |
| 03/31/2015 | Affimed N.V. | AFMD | 400,000 | 400,000 | 2,520,000 | 2,520,000 | $6.30 |
| 12/31/2014 | Affimed N.V. | AFMD | 400,000 | 400,000 | 2,480,000 | 2,480,000 | $6.20 |
| 09/30/2014 | Affimed N.V. | AFMD | 400,000 | 400,000 | 2,520,000 | 2,520,000 | $6.30 |
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