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Novo Holdings A/S
> SPRO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Spero Therapeutics, Inc. | SPRO | 468,902 | 0 | 679,908,000 | 0 | $1,450.00 |
| 03/31/2023 | Spero Therapeutics, Inc. | SPRO | 468,902 | 0 | 679,908,000 | 678,970,000 | $1,450.00 |
| 09/30/2022 | Spero Therapeutics, Inc. | SPRO | 468,902 | 0 | 938,000 | 591,000 | $2.00 |
| 06/30/2022 | Spero Therapeutics, Inc. | SPRO | 468,902 | 0 | 347,000 | -3,732,000 | $0.74 |
| 03/31/2022 | Spero Therapeutics, Inc. | SPRO | 468,902 | 0 | 4,079,000 | -3,428,000 | $8.70 |
| 12/31/2021 | Spero Therapeutics, Inc. | SPRO | 468,902 | 0 | 7,507,000 | -1,125,000 | $16.01 |
| 09/30/2021 | Spero Therapeutics, Inc. | SPRO | 468,902 | 0 | 8,632,000 | 2,086,000 | $18.41 |
| 06/30/2021 | Spero Therapeutics, Inc. | SPRO | 468,902 | -107,800 | 6,546,000 | -4,636,000 | $13.96 |
| 12/31/2020 | Spero Therapeutics, Inc. | SPRO | 576,702 | -354,397 | 11,182,000 | 791,000 | $19.39 |
| 09/30/2020 | Spero Therapeutics, Inc. | SPRO | 931,099 | 0 | 10,391,000 | -2,207,000 | $11.16 |
| 06/30/2020 | Spero Therapeutics, Inc. | SPRO | 931,099 | 0 | 12,598,000 | 5,075,000 | $13.53 |
| 03/31/2020 | Spero Therapeutics, Inc. | SPRO | 931,099 | 0 | 7,523,000 | -1,425,000 | $8.08 |
| 12/31/2019 | Spero Therapeutics, Inc. | SPRO | 931,099 | 465,116 | 8,948,000 | 4,009,000 | $9.61 |
| 09/30/2019 | Spero Therapeutics, Inc. | SPRO | 465,983 | 0 | 4,939,000 | -424,000 | $10.60 |
| 06/30/2019 | Spero Therapeutics, Inc. | SPRO | 465,983 | 465,983 | 5,363,000 | 5,363,000 | $11.51 |
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