The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ACUTUS MED INC | COM | 005111109 | 2,254 | 255,000 | SH | SOLE | 255,000 | 0 | 0 | ||
| AERIE PHARMACEUTICALS INC | COM | 00771V108 | 6,329 | 555,186 | SH | SOLE | 555,186 | 0 | 0 | ||
| AKOUOS INC | COM | 00973J101 | 8,266 | 711,945 | SH | SOLE | 711,945 | 0 | 0 | ||
| ALIBABA GROUP HLDG LTD | SPONSORED ADS | 01609W102 | 31,805 | 214,827 | SH | SOLE | 214,827 | 0 | 0 | ||
| ALIGOS THERAPEUTICS INC | COM | 01626L105 | 40,552 | 2,614,563 | SH | SOLE | 2,614,563 | 0 | 0 | ||
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 4,720 | 25,000 | SH | SOLE | 25,000 | 0 | 0 | ||
| AMICUS THERAPEUTICS INC | COM | 03152W109 | 24,450 | 2,560,211 | SH | SOLE | 2,560,211 | 0 | 0 | ||
| ANNEXON INC | COM | 03589W102 | 2,128 | 114,330 | SH | SOLE | 114,330 | 0 | 0 | ||
| APPLE INC | COM | 037833100 | 146,793 | 1,037,404 | SH | SOLE | 1,037,404 | 0 | 0 | ||
| BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 20,254 | 197,000 | SH | SOLE | 197,000 | 0 | 0 | ||
| BOLT BIOTHERAPEUTICS INC | COM | 097702104 | 56,975 | 4,503,991 | SH | SOLE | 4,503,991 | 0 | 0 | ||
| BOSTON SCIENTIFIC CORP | COM | 101137107 | 150,285 | 3,463,577 | SH | SOLE | 3,463,577 | 0 | 0 | ||
| BROOKFIELD ASSET MGMT INC | CL A LTD VT SH | 112585104 | 165,516 | 3,093,171 | SH | SOLE | 3,093,171 | 0 | 0 | ||
| CABLE ONE INC | COM | 12685J105 | 28,780 | 15,873 | SH | SOLE | 15,873 | 0 | 0 | ||
| CHECKMATE PHARMACEUTICALS IN | COM | 162818108 | 8,615 | 2,170,100 | SH | SOLE | 2,170,100 | 0 | 0 | ||
| CYTEIR THERAPEUTICS INC | COM | 23284P103 | 84,949 | 4,840,413 | SH | SOLE | 4,840,413 | 0 | 0 | ||
| EDGEWISE THERAPEUTICS INC | COM | 28036F105 | 92,748 | 5,587,207 | SH | SOLE | 5,587,207 | 0 | 0 | ||
| F-STAR THERAPEUTICS INC | COM | 30315R107 | 20 | 2,703 | SH | SOLE | 2,703 | 0 | 0 | ||
| FLEXION THERAPEUTICS INC | COM | 33938J106 | 8,561 | 1,403,370 | SH | SOLE | 1,403,370 | 0 | 0 | ||
| FREELINE THERAPEUTICS HLDGS | SPONSORED ADS | 35655L107 | 6,575 | 1,928,157 | SH | SOLE | 1,928,157 | 0 | 0 | ||
| GALECTO INC | COM | 36322Q107 | 8,967 | 2,497,791 | SH | SOLE | 2,497,791 | 0 | 0 | ||
| GALERA THERAPEUTICS INC | COM | 36338D108 | 19,918 | 2,459,021 | SH | SOLE | 2,459,021 | 0 | 0 | ||
| HARMONY BIOSCIENCES HLDGS IN | COM | 413197104 | 1,533 | 40,000 | SH | SOLE | 40,000 | 0 | 0 | ||
| INARI MED INC | COM | 45332Y109 | 5,856 | 72,212 | SH | SOLE | 72,212 | 0 | 0 | ||
| INOGEN INC | COM | 45780L104 | 46,508 | 1,079,320 | SH | SOLE | 1,079,320 | 0 | 0 | ||
| INSMED INC | COM PAR $.01 | 457669307 | 19,163 | 695,840 | SH | SOLE | 695,840 | 0 | 0 | ||
| INSPIRE MED SYS INC | COM | 457730109 | 4,960 | 21,300 | SH | SOLE | 21,300 | 0 | 0 | ||
| IOVANCE BIOTHERAPEUTICS INC | COM | 462260100 | 20,629 | 836,518 | SH | SOLE | 836,518 | 0 | 0 | ||
| KINNATE BIOPHARMA INC | COM | 49705R105 | 11,476 | 498,528 | SH | SOLE | 498,528 | 0 | 0 | ||
| LAVA THERAPEUTICS NV | SHS | N51517105 | 19,698 | 3,327,312 | SH | SOLE | 3,327,312 | 0 | 0 | ||
| MILESTONE PHARMACEUTICALS IN | COM | 59935V107 | 14,450 | 2,530,585 | SH | SOLE | 2,530,585 | 0 | 0 | ||
| MIRUM PHARMACEUTICALS INC | COM | 604749101 | 48,707 | 2,445,147 | SH | SOLE | 2,445,147 | 0 | 0 | ||
| MORPHIC HLDG INC | COM | 61775R105 | 116,137 | 2,050,446 | SH | SOLE | 2,050,446 | 0 | 0 | ||
| NKARTA INC | COM | 65487U108 | 77,697 | 2,793,864 | SH | SOLE | 2,793,864 | 0 | 0 | ||
| PHARVARIS N V | COM | N69605108 | 7,428 | 418,943 | SH | SOLE | 418,943 | 0 | 0 | ||
| PRAXIS PRECISION MEDICINES I | COM | 74006W108 | 4,623 | 250,000 | SH | SOLE | 250,000 | 0 | 0 | ||
| PULMONX CORP | COM | 745848101 | 8,889 | 247,047 | SH | SOLE | 247,047 | 0 | 0 | ||
| RENEO PHARMACEUTICALS INC | COM | 75974E103 | 25,556 | 3,430,377 | SH | SOLE | 3,430,377 | 0 | 0 | ||
| ROCKET PHARMACEUTICALS INC | COM | 77313F106 | 15,964 | 534,085 | SH | SOLE | 534,085 | 0 | 0 | ||
| SEASPINE HLDGS CORP | COM | 81255T108 | 17,295 | 1,099,478 | SH | SOLE | 1,099,478 | 0 | 0 | ||
| SILK RD MED INC | COM | 82710M100 | 8,120 | 147,557 | SH | SOLE | 147,557 | 0 | 0 | ||
| SPERO THERAPEUTICS INC | COM | 84833T103 | 8,632 | 468,902 | SH | SOLE | 468,902 | 0 | 0 | ||
| SPRUCE BIOSCIENCES INC | COM | 85209E109 | 27,131 | 4,514,336 | SH | SOLE | 4,514,336 | 0 | 0 | ||
| TREACE MED CONCEPTS INC | COM | 89455T109 | 7,633 | 283,769 | SH | SOLE | 283,769 | 0 | 0 | ||
| VANGUARD INDEX FDS | TOTAL STK MKT | 922908769 | 429,442 | 1,933,900 | SH | SOLE | 1,933,900 | 0 | 0 | ||
| VECTIVBIO HLDG AG | ORD SHS | H9060V101 | 27,190 | 3,522,019 | SH | SOLE | 3,522,019 | 0 | 0 | ||
| VERONA PHARMA PLC | SPONSORED ADS | 925050106 | 4,171 | 761,205 | SH | SOLE | 761,205 | 0 | 0 | ||
| VERVE THERAPEUTICS INC | COM | 92539P101 | 28,200 | 600,000 | SH | SOLE | 600,000 | 0 | 0 | ||
| ZOGENIX INC | COM NEW | 98978L204 | 6,722 | 442,550 | SH | SOLE | 442,550 | 0 | 0 | ||