The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108 4,730 119,708 SH   SOLE   119,708 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 12,878 670,036 SH   SOLE   670,036 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 12,152 3,100,000 SH   SOLE   3,100,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109 18,589 2,317,870 SH   SOLE   2,317,870 0 0
APPLE INC COM 037833100 59,976 267,788 SH   SOLE   267,788 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 1,498 35,900 SH   SOLE   35,900 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 12,539 170,667 SH   SOLE   170,667 0 0
CABLE ONE INC COM 12685J105 56,462 45,000 SH   SOLE   45,000 0 0
CORVUS PHARMACEUTICALS INC COM 221015100 8,812 2,927,560 SH   SOLE   2,927,560 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 2,031 135,009 SH   SOLE   135,009 0 0
ENTASIS THERAPEUTICS HLDGS I COM 293614103 13,004 2,181,843 SH   SOLE   2,181,843 0 0
FLEXION THERAPEUTICS INC COM 33938JAB2 6,170 450,000 SH   SOLE   450,000 0 0
INOGEN INC COM 45780L104 170,048 3,549,321 SH   SOLE   3,549,321 0 0
INSPIRE MED SYS INC COM 457730109 10,679 175,000 SH   SOLE   175,000 0 0
INTERSECT ENT INC COM 46071F103 3,703 217,709 SH   SOLE   217,709 0 0
MILESTONE PHARMACEUTICALS INC COM 59935V107 49,879 2,674,470 SH   SOLE   2,674,470 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 24,598 2,445,147 SH   SOLE   2,445,147 0 0
MORPHIC HLDG INC COM 61775R105 47,909 2,645,446 SH   SOLE   2,645,446 0 0
MYOKARDIA INC COM 62857M105 1,583 30,348 SH   SOLE   30,348 0 0
NEURONETICS INC COM 64131A105 5,222 628,348 SH   SOLE   628,348 0 0
ORTHOPEDIATRICS CORP COM 68752L100 5,333 151,259 SH   SOLE   151,259 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 5,754 479,074 SH   SOLE   479,074 0 0
SEASPINE HLDGS CORP COM 81255T108 15,971 1,308,037 SH   SOLE   1,308,037 0 0
SI BONE INC COM 825704109 15,774 892,684 SH   SOLE   892,684 0 0
SILK ROAD MEDICAL INC COM 82710M100 7,970 245,000 SH   SOLE   245,000 0 0
SPERO THERAPEUTICS INC COM 84833T103 4,939 465,983 SH   SOLE   465,983 0 0
UNUM THERAPEUTICS INC COM 903214104 682 473,441 SH   SOLE   473,441 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106 3,385 740,740 SH   SOLE   740,740 0 0
ZOGENIX INC COM NEW 98978L204 1,429 35,700 SH   SOLE   35,700 0 0