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BAKER BROS. ADVISORS LP
> TSVT
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | 2seventy bio, Inc. | TSVT | 2,497,526 | 434,782 | 25,274,963,000 | 5,947,052,000 | $10,120.00 |
| 12/31/2022 | 2seventy bio, Inc. | TSVT | 2,062,744 | 0 | 19,327,911,000 | 19,297,898,000 | $9,370.00 |
| 09/30/2022 | 2seventy bio, Inc. | TSVT | 2,062,744 | 0 | 30,013,000 | 2,785,000 | $14.55 |
| 06/30/2022 | 2seventy bio, Inc. | TSVT | 2,062,744 | 0 | 27,228,000 | -7,962,000 | $13.20 |
| 03/31/2022 | 2seventy bio, Inc. | TSVT | 2,062,744 | 1,229,508 | 35,190,000 | 13,834,000 | $17.06 |
| 12/31/2021 | 2seventy bio, Inc. | TSVT | 833,236 | 833,236 | 21,356,000 | 21,356,000 | $25.63 |
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