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EcoR1 Capital, LLC
> PRTA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | PROTHENA CORP PUBLIC LTD CO | PRTA | 11,584,280 | 0 | 790,974,638,000 | 229,484,586,000 | $68,280.00 |
| 03/31/2023 | PROTHENA CORP PUBLIC LTD CO | PRTA | 11,584,280 | 0 | 561,490,052,000 | -136,462,818,000 | $48,470.00 |
| 12/31/2022 | PROTHENA CORP PUBLIC LTD CO | PRTA | 11,584,280 | 0 | 697,952,870,000 | 697,250,515,000 | $60,250.00 |
| 09/30/2022 | PROTHENA CORP PUBLIC LTD CO | PRTA | 11,584,280 | 0 | 702,355,000 | 387,842,000 | $60.63 |
| 06/30/2022 | PROTHENA CORP PUBLIC LTD CO | PRTA | 11,584,280 | 0 | 314,513,000 | -109,124,000 | $27.15 |
| 03/31/2022 | PROTHENA CORP PUBLIC LTD CO | PRTA | 11,584,280 | 300,000 | 423,637,000 | -133,806,000 | $36.57 |
| 12/31/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | 11,284,280 | 0 | 557,443,000 | -246,336,000 | $49.40 |
| 09/30/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | 11,284,280 | 0 | 803,779,000 | 223,654,000 | $71.23 |
| 06/30/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | 11,284,280 | 250,000 | 580,125,000 | 302,944,000 | $51.41 |
| 03/31/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | 11,034,280 | 1,607,640 | 277,181,000 | 163,967,000 | $25.12 |
| 12/31/2020 | PROTHENA CORP PUBLIC LTD CO | PRTA | 9,426,640 | 0 | 113,214,000 | 19,042,000 | $12.01 |
| 09/30/2020 | PROTHENA CORP PUBLIC LTD CO | PRTA | 9,426,640 | 0 | 94,172,000 | -4,431,000 | $9.99 |
| 06/30/2020 | PROTHENA CORP PUBLIC LTD CO | PRTA | 9,426,640 | 0 | 98,603,000 | -2,262,000 | $10.46 |
| 03/31/2020 | PROTHENA CORP PUBLIC LTD CO | PRTA | 9,426,640 | 0 | 100,865,000 | -48,359,000 | $10.70 |
| 12/31/2019 | PROTHENA CORP PUBLIC LTD CO | PRTA | 9,426,640 | 0 | 149,224,000 | 75,319,000 | $15.83 |
| 09/30/2019 | PROTHENA CORP PUBLIC LTD CO | PRTA | 9,426,640 | 8,703,340 | 73,905,000 | 66,260,000 | $7.84 |
| 06/30/2019 | PROTHENA CORP PUBLIC LTD CO | PRTA | 723,300 | -3,219 | 7,645,000 | -1,168,000 | $10.57 |
| 03/31/2019 | PROTHENA CORP PUBLIC LTD CO | PRTA | 726,519 | -111,700 | 8,813,000 | 179,000 | $12.13 |
| 12/31/2018 | PROTHENA CORP PUBLIC LTD CO | PRTA | 838,219 | 838,219 | 8,634,000 | 8,634,000 | $10.30 |
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