The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
5 01 ACQUISITION CORP COM 33836P105 2,034 200,000 SH   SOLE   200,000 0 0
AC IMMUNE SA SHS H00263105 12,461 2,410,240 SH   SOLE   2,410,240 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 9,768 1,509,812 SH   SOLE   1,509,812 0 0
AKOUOS INC COM 00973J101 39,184 1,975,984 SH   SOLE   1,975,984 0 0
ALLOVIR INC COM 019818103 17,183 447,012 SH   SOLE   447,012 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 9,340 741,290 SH   SOLE   741,290 0 0
ANAPTYSBIO INC COM 032724106 69,301 3,223,324 SH   SOLE   3,223,324 0 0
APPLIED MOLECULAR TRANS INC COM 03824M109 35,386 1,150,000 SH   SOLE   1,150,000 0 0
ARCUS BIOSCIENCES INC COM 03969F109 57,005 2,195,892 SH   SOLE   2,195,892 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 108 17,800 SH Call SOLE   17,800 0 0
ATRECA INC CL A COM 04965G109 39,191 2,426,685 SH   SOLE   2,426,685 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 53,693 2,103,950 SH   SOLE   2,103,950 0 0
BCLS ACQUISITION CORP COM G0904B105 2,228 200,000 SH   SOLE   200,000 0 0
BCTG ACQUISITION CORP COM 05492W103 9,152 800,000 SH   SOLE   800,000 0 0
BIOATLA INC COM 09077B104 1,701 50,000 SH   SOLE   50,000 0 0
BIOGEN INC COM 09062X103 48,972 200,000 SH Call SOLE   200,000 0 0
BIOGEN INC COM 09062X103 13,247 54,100 SH Call SOLE   54,100 0 0
C4 THERAPEUTICS INC COM 12529R107 6,626 200,000 SH   SOLE   200,000 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 6,632 400,000 SH   SOLE   400,000 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 19,825 1,250,001 SH   SOLE   1,250,001 0 0
CODIAK BIOSCIENCES INC COM 192010106 3,721 115,195 SH   SOLE   115,195 0 0
CONSONANCE HFW ACQUISITION C UNIT G2445M129 2,094 200,000 SH   SOLE   200,000 0 0
CYCLERION THERAPEUTICS INC COM 23255M105 4,915 1,606,276 SH   SOLE   1,606,276 0 0
DEERFIELD HEALTHCARE TECH AC COM 244413100 7,513 481,600 SH   SOLE   481,600 0 0
DEERFIELD HEALTHCARE TECH AC *W EXP 244413118 1,560 100,000 SH   SOLE   100,000 0 0
DYNE THERAPEUTICS INC COM 26818M108 4,515 215,000 SH   SOLE   215,000 0 0
EUCRATES BIOMEDICAL ACQU COR UNIT G3141W114 2,132 200,000 SH   SOLE   200,000 0 0
FRAZIER LIFESCIENCES ACQU CO UNIT G3710A121 2,076 200,000 SH   SOLE   200,000 0 0
GALAPAGOS NV SPON ADR 36315X101 4,619 46,666 SH   SOLE   46,666 0 0
GERON CORP COM 374163103 30,114 18,939,925 SH   SOLE   18,939,925 0 0
GOSSAMER BIO INC NOTE 38341PAA0 27,175 30,000,000 PRN   SOLE   30,000,000 0 0
GOSSAMER BIO INC COM 38341P102 2,845 294,221 SH   SOLE   294,221 0 0
GRITSTONE ONCOLOGY INC COM 39868T105 13,480 3,421,287 SH   SOLE   3,421,287 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 5,124 400,000 SH   SOLE   400,000 0 0
HELIX ACQUISITION CORP COM G4444C102 2,274 200,000 SH   SOLE   200,000 0 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108 625 25,300 SH Call SOLE   25,300 0 0
ITEOS THERAPEUTICS INC COM 46565G104 8,793 260,000 SH   SOLE   260,000 0 0
JIYA ACQUISITION CORP COM 47760M102 5,150 500,000 SH   SOLE   500,000 0 0
KINNATE BIOPHARMA INC COM 49705R105 995 25,000 SH   SOLE   25,000 0 0
KRONOS BIO INC COM 50107A104 11,570 387,357 SH   SOLE   387,357 0 0
KURA ONCOLOGY INC COM 50127T109 57,907 1,773,037 SH   SOLE   1,773,037 0 0
KYMERA THERAPEUTICS INC COM 501575104 6,200 100,000 SH   SOLE   100,000 0 0
LIFESCI ACQUISITION II CORP COM 53229E103 2,134 200,000 SH   SOLE   200,000 0 0
LOGICBIO THERAPEUTICS INC COM 54142F102 5,913 775,000 SH   SOLE   775,000 0 0
MEIRAGTX HLDGS PLC COM G59665102 1,436 94,819 SH   SOLE   94,819 0 0
METACRINE INC COM 59101E103 2,620 333,332 SH   SOLE   333,332 0 0
MIRATI THERAPEUTICS INC COM 60468T105 101,978 464,298 SH   SOLE   464,298 0 0
MORPHIC HLDG INC COM 61775R105 95,278 2,839,884 SH   SOLE   2,839,884 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 44,030 3,122,704 SH   SOLE   3,122,704 0 0
NGM BIOPHARMACEUTICALS INC COM 62921N105 4,349 143,567 SH   SOLE   143,567 0 0
NURIX THERAPEUTICS INC COM 67080M103 50,767 1,544,019 SH   SOLE   1,544,019 0 0
ORIC PHARMACEUTICALS INC COM 68622P109 104,672 3,092,218 SH   SOLE   3,092,218 0 0
PANACEA ACQUISITION CORP UNIT 99/99/9999 698102209 4,977 390,000 SH   SOLE   390,000 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 3,076 50,000 SH   SOLE   50,000 0 0
PROTHENA CORP PLC SHS G72800108 113,214 9,426,640 SH   SOLE   9,426,640 0 0
RELAY THERAPEUTICS INC COM 75943R102 133,019 3,200,649 SH   SOLE   3,200,649 0 0
REPARE THERAPEUTICS INC COM 760273102 1,715 50,000 SH   SOLE   50,000 0 0
SHATTUCK LABS INC COM 82024L103 128,764 2,456,854 SH   SOLE   2,456,854 0 0
SILVERBACK THERAPEUTICS INC COM 82835W108 117,409 2,533,635 SH   SOLE   2,533,635 0 0
SOLID BIOSCIENCES INC COM 83422E105 60,471 7,977,702 SH   SOLE   7,977,702 0 0
SURFACE ONCOLOGY INC COM 86877M209 449 48,558 SH   SOLE   48,558 0 0
SUTRO BIOPHARMA INC COM 869367102 2,028 93,416 SH   SOLE   93,416 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 10,850 1,000,000 SH   SOLE   1,000,000 0 0
TURMERIC ACQUISITION CORP UNIT G9127T116 1,027 100,000 SH   SOLE   100,000 0 0
VINCERA PHARMA INC COM 92731L106 10,047 480,505 SH   SOLE   480,505 0 0
VINCERA PHARMA INC *W EXP 92731L114 3,137 150,000 SH   SOLE   150,000 0 0
XENCOR INC COM 98401F105 198,389 4,547,072 SH   SOLE   4,547,072 0 0