The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ASSEMBLY BIOSCIENCES ORD COM 045396108 2,711 275,800 SH Call SOLE   275,800 0 0
ASSEMBLY BIOSCIENCES ORD COM 045396108 2,187 222,500 SH Call SOLE   222,500 0 0
FIBROGEN ORD COM 31572Q808 13,868 375,000 SH Call SOLE   375,000 0 0
FIBROGEN ORD COM 31572Q808 10,262 277,500 SH Call SOLE   277,500 0 0
GOSSAMER BIO INC ORD COM 38341P102 3,358 200,000 SH Call SOLE   200,000 0 0
GOSSAMER BIO INC ORD COM 38341P102 10,074 600,000 SH Call SOLE   600,000 0 0
ARCUS BIOSCIENCES ORD COM 03969F109 6,866 754,505 SH   SOLE   754,505 0 0
ASSEMBLY BIOSCIENCES ORD COM 045396108 950 96,600 SH   SOLE   96,600 0 0
ATRECA CL A ORD COM 04965G109 18,132 1,481,411 SH   SOLE   1,481,411 0 0
CHIASMA ORD COM 16706W102 15,067 3,043,827 SH   SOLE   3,043,827 0 0
CORTEXYME ORD COM 22053A107 1,246 49,993 SH   SOLE   49,993 0 0
CURIS ORD COM 231269200 6,680 2,982,208 SH   SOLE   2,982,208 0 0
CYCLERION THERAPEUTICS ORD COM 23255M105 9,408 776,206 SH   SOLE   776,206 0 0
DICERNA PHARMACEUTICALS ORD COM 253031108 56,908 3,962,978 SH   SOLE   3,962,978 0 0
EIGER BIOPHARMACEUTICAL ORD COM 28249U105 10,865 1,060,043 SH   SOLE   1,060,043 0 0
EXICURE ORD COM 30205M101 13,954 5,515,225 SH   SOLE   5,515,225 0 0
FIBROGEN ORD COM 31572Q808 47,845 1,293,807 SH   SOLE   1,293,807 0 0
HARPOON THERAPEUTICS ORD COM 41358P106 19,990 1,463,423 SH   SOLE   1,463,423 0 0
IGM BIOSCIENCES ORD COM 449585108 1,775 100,000 SH   SOLE   100,000 0 0
IRONWOOD PHARMA CL A ORD COM 46333X108 40,104 4,671,408 SH   SOLE   4,671,408 0 0
KURA ONCOLOGY ORD COM 50127T109 61,316 4,041,953 SH   SOLE   4,041,953 0 0
MERUS ORD COM N5749R100 2,951 165,600 SH   SOLE   165,600 0 0
MIRATI THERAPEUTICS ORD COM 60468T105 3,445 44,221 SH   SOLE   44,221 0 0
MORPHIC HOLDING ORD COM 61775R105 39,145 2,161,520 SH   SOLE   2,161,520 0 0
NEOLEUKIN THERAPEUTICS ORD COM 64049K104 6,458 2,265,880 SH   SOLE   2,265,880 0 0
NEXTCURE ORD COM 65343E108 7,728 250,500 SH   SOLE   250,500 0 0
PREVAIL THERAPEUTICS ORD COM 74140Y101 29,381 2,392,556 SH   SOLE   2,392,556 0 0
PROTHENA ORD COM G72800108 73,905 9,426,640 SH   SOLE   9,426,640 0 0
REGULUS THERAPEUTICS ORD COM 75915K200 755 1,049,088 SH   SOLE   1,049,088 0 0
RUBIUS THERAPEUTICS ORD COM 78116T103 2,042 260,152 SH   SOLE   260,152 0 0
SAREPTA THERAPEUTICS ORD COM 803607100 14,292 189,745 SH   SOLE   189,745 0 0
SOLID BIOSCIENCES ORD COM 83422E105 34,563 3,342,691 SH   SOLE   3,342,691 0 0
SPARK THERAPEUTICS ORD COM 84652J103 69,320 714,789 SH   SOLE   714,789 0 0
SURFACE ONCOLOGY ORD COM 86877M209 2,199 1,548,888 SH   SOLE   1,548,888 0 0
ULTRAGENYX PHARMACEUTICAL ORD COM 90400D108 2,633 61,554 SH   SOLE   61,554 0 0
UNITY BIOTECHNOLOGY ORD COM 91381U101 314 51,400 SH   SOLE   51,400 0 0
VERICEL ORD COM 92346J108 1,983 131,001 SH   SOLE   131,001 0 0
XENCOR ORD COM 98401F105 84,378 2,501,557 SH   SOLE   2,501,557 0 0
ZAFGEN ORD COM 98885E103 1,437 1,944,500 SH   SOLE   1,944,500 0 0
ARGENX ADR REP ORD SPONSORED ADR 04016X101 60,532 531,165 SH   SOLE   531,165 0 0
AUTOLUS THERAPEUTICS ADR SPONSORED ADR 05280R100 859 69,155 SH   SOLE   69,155 0 0