The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
2SEVENTY BIO INC COMMON STOCK 901384107 46,146 3,495,943 SH   SOLE   3,495,943 0 0
5 01 ACQUISITION CORP COM CL A 33836P105 1,980 200,000 SH   SOLE   200,000 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 84,420 5,991,479 SH   SOLE   5,991,479 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 1,256 1,046,700 SH   SOLE   1,046,700 0 0
AKOUOS INC COM 00973J101 9,267 1,975,984 SH   SOLE   1,975,984 0 0
ALECTOR INC COM 014442107 41,215 4,056,548 SH   SOLE   4,056,548 0 0
ALIGOS THERAPEUTICS INC COM 01626L105 4,778 3,948,360 SH   SOLE   3,948,360 0 0
ALLOGENE THERAPEUTICS INC COM 019770106 51,165 4,488,200 SH   SOLE   4,488,200 0 0
ANAPTYSBIO INC COM 032724106 152,677 7,521,024 SH   SOLE   7,521,024 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 234,395 5,183,431 SH   SOLE   5,183,431 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 19,083 895,503 SH   SOLE   895,503 0 0
ARGENX SE SPONSORED ADR 04016X101 47,360 125,000 SH   SOLE   125,000 0 0
ARVINAS INC COM 04335A105 131,460 3,123,300 SH   SOLE   3,123,300 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108 1,472 150,000 SH   SOLE   150,000 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 45,019 6,340,639 SH   SOLE   6,340,639 0 0
AVEO PHARMACEUTICALS INC COM NEW 053588307 4,248 647,489 SH   SOLE   647,489 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 40,096 2,759,505 SH   SOLE   2,759,505 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 1,980 200,000 SH   SOLE   200,000 0 0
BOLT BIOTHERAPEUTICS INC COM 097702104 306 150,000 SH   SOLE   150,000 0 0
CAREMAX INC *W EXP 06/08/202 14171W111 363 100,000 SH   SOLE   100,000 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 3,106 115,200 SH Put SOLE   115,200 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100 1,424 292,320 SH   SOLE   292,320 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 43,527 1,646,260 SH   SOLE   1,646,260 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 12,068 690,000 SH   SOLE   690,000 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 24,809 1,330,263 SH   SOLE   1,330,263 0 0
CULLINAN ONCOLOGY INC COM 230031106 14,998 1,169,889 SH   SOLE   1,169,889 0 0
DESIGN THERAPEUTICS INC COM 25056L103 36,878 2,634,178 SH   SOLE   2,634,178 0 0
DYNE THERAPEUTICS INC COM 26818M108 1,477 215,000 SH   SOLE   215,000 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 18,784 2,359,808 SH   SOLE   2,359,808 0 0
ERASCA INC COM 29479A108 3,779 678,441 SH   SOLE   678,441 0 0
EUCRATES BIOMEDICAL ACQU COR SHS G3141W106 1,980 200,000 SH   SOLE   200,000 0 0
EUCRATES BIOMEDICAL ACQU COR *W EXP 10/23/202 G3141W122 660 66,666 SH   SOLE   66,666 0 0
EVELO BIOSCIENCES INC COM 299734103 423 200,417 SH   SOLE   200,417 0 0
EXELIXIS INC COM 30161Q104 15,823 760,000 SH Call SOLE   760,000 0 0
FRAZIER LIFESCIENCES ACQU CO *W EXP 11/30/202 G3710A113 658 66,665 SH   SOLE   66,665 0 0
FRAZIER LIFESCIENCES ACQU CO CL A SHS G3710A105 5,800 587,615 SH   SOLE   587,615 0 0
GALAPAGOS NV SPON ADR 36315X101 178,420 3,197,500 SH   SOLE   3,197,500 0 0
GERON CORP COM 374163103 21,962 14,168,988 SH   SOLE   14,168,988 0 0
GRACELL BIOTECHNOLOGIES INC SPONSORED ADS 38406L103 10,567 1,921,310 SH   SOLE   1,921,310 0 0
GRAPHITE BIO INC COM 38870X104 3,196 1,162,179 SH   SOLE   1,162,179 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 3,984 400,000 SH   SOLE   400,000 0 0
HOOKIPA PHARMA INC COM 43906K100 8,150 5,000,000 SH   SOLE   5,000,000 0 0
INCYTE CORP COM 45337C102 13,886 182,783 SH   SOLE   182,783 0 0
ITEOS THERAPEUTICS INC COM 46565G104 5,768 279,999 SH   SOLE   279,999 0 0
JANUX THERAPEUTICS INC COM 47103J105 17,354 1,421,319 SH   SOLE   1,421,319 0 0
JIYA ACQUISITION CORP COM CL A 47760M102 4,940 500,000 SH   SOLE   500,000 0 0
KINNATE BIOPHARMA INC COM 49705R105 2,207 175,000 SH   SOLE   175,000 0 0
KRONOS BIO INC COM 50107A104 1,189 326,780 SH   SOLE   326,780 0 0
KURA ONCOLOGY INC COM 50127T109 121,681 6,638,371 SH   SOLE   6,638,371 0 0
MERSANA THERAPEUTICS INC COM 59045L106 1,437 310,960 SH   SOLE   310,960 0 0
MORPHIC HLDG INC COM 61775R105 85,749 3,951,566 SH   SOLE   3,951,566 0 0
NGM BIOPHARMACEUTICALS INC COM 62921N105 6,937 541,108 SH   SOLE   541,108 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 3,121 963,333 SH   SOLE   963,333 0 0
NUVATION BIO INC COM CL A 67080N101 45,025 13,896,543 SH   SOLE   13,896,543 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106 1,440 353,701 SH   SOLE   353,701 0 0
OMEGA ALPHA SPAC CL A G6749V107 493 50,000 SH   SOLE   50,000 0 0
ORIC PHARMACEUTICALS INC COM 68622P109 15,313 3,418,068 SH   SOLE   3,418,068 0 0
OVID THERAPEUTICS INC COM 690469101 13,152 6,117,400 SH   SOLE   6,117,400 0 0
PARDES BIOSCIENCES INC COM 69945Q105 614 200,000 SH   SOLE   200,000 0 0
PRAXIS PRECISION MEDICINES I COM 74006W108 515 210,100 SH   SOLE   210,100 0 0
PRECISION BIOSCIENCES INC COM 74019P108 8,058 5,035,971 SH   SOLE   5,035,971 0 0
PROTHENA CORP PLC SHS G72800108 314,513 11,584,280 SH   SOLE   11,584,280 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 60,039 1,975,611 SH   SOLE   1,975,611 0 0
RELAY THERAPEUTICS INC COM 75943R102 62,369 3,723,541 SH   SOLE   3,723,541 0 0
REVOLUTION MEDICINES INC COM 76155X100 83,380 4,278,069 SH   SOLE   4,278,069 0 0
SAREPTA THERAPEUTICS INC COM 803607100 214,996 2,868,145 SH   SOLE   2,868,145 0 0
SEAGEN INC COM 81181C104 178,467 1,008,628 SH   SOLE   1,008,628 0 0
SELECTA BIOSCIENCES INC COM 816212104 4,585 3,500,000 SH   SOLE   3,500,000 0 0
SILVERBACK THERAPEUTICS INC COM 82835W108 2,440 575,359 SH   SOLE   575,359 0 0
SURFACE ONCOLOGY INC COM 86877M209 7,631 4,653,000 SH   SOLE   4,653,000 0 0
SURROZEN INC *W EXP 08/01/203 86889P117 200 66,665 SH   SOLE   66,665 0 0
TANGO THERAPEUTICS INC COM 87583X109 10,428 2,302,065 SH   SOLE   2,302,065 0 0
TEMPEST THERAPEUTICS INC COM 87978U108 2,217 1,031,268 SH   SOLE   1,031,268 0 0
TURMERIC ACQUISITION CORP CL A G9127T108 993 100,000 SH   SOLE   100,000 0 0
TURMERIC ACQUISITION CORP *W EXP 10/08/202 G9127T124 331 33,333 SH   SOLE   33,333 0 0
VENTYX BIOSCIENCES INC COM 92332V107 15,899 1,300,000 SH   SOLE   1,300,000 0 0
VERVE THERAPEUTICS INC COM 92539P101 1,507 98,593 SH   SOLE   98,593 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 28,096 4,753,907 SH   SOLE   4,753,907 0 0
XENCOR INC COM 98401F105 144,580 5,282,416 SH   SOLE   5,282,416 0 0
ZAI LAB LT ADR 98887Q104 84,338 2,431,885 SH   SOLE   2,431,885 0 0