The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
FIBROGEN ORD COM 31572Q808 12,537 277,500 SH Call SOLE   277,500 0 0
ASSEMBLY BIOSCIENCES ORD COM 045396108 3,721 275,800 SH Call SOLE   275,800 0 0
ASSEMBLY BIOSCIENCES ORD COM 045396108 3,002 222,500 SH Call SOLE   222,500 0 0
KURA ONCOLOGY ORD COM 50127T109 103,899 5,276,753 SH   SOLE   5,276,753 0 0
XENCOR ORD COM 98401F105 95,635 2,336,557 SH   SOLE   2,336,557 0 0
CRISPR THERAPEUTICS ORD COM H17182108 75,843 1,610,250 SH   SOLE   1,610,250 0 0
FIBROGEN ORD COM 31572Q808 68,302 1,511,785 SH   SOLE   1,511,785 0 0
SPARK THERAPEUTICS ORD COM 84652J103 62,874 614,128 SH   SOLE   614,128 0 0
MIRATI THERAPEUTICS ORD COM 60468T105 61,564 597,711 SH   SOLE   597,711 0 0
DICERNA PHARMACEUTICALS ORD COM 253031108 52,233 3,316,407 SH   SOLE   3,316,407 0 0
IRONWOOD PHARMA CL A ORD COM 46333X108 51,105 4,671,408 SH   SOLE   4,671,408 0 0
ULTRAGENYX PHARMACEUTICAL ORD COM 90400D108 31,617 497,899 SH   SOLE   497,899 0 0
CHIASMA ORD COM 16706W102 22,737 3,043,827 SH   SOLE   3,043,827 0 0
MORPHIC HOLDING ORD COM 61775R105 44,928 2,266,804 SH   SOLE   947,618 0 0
HARPOON THERAPEUTICS ORD COM 41358P106 17,529 1,348,423 SH   SOLE   1,348,423 0 0
ATRECA CL A ORD COM 04965G109 28,015 1,486,979 SH   SOLE   771,672 0 0
ARQULE ORD COM 04269E107 14,313 1,300,000 SH   SOLE   1,300,000 0 0
EIGER BIOPHARMACEUTICAL ORD COM 28249U105 12,042 1,136,043 SH   SOLE   1,136,043 0 0
ARCUS BIOSCIENCES ORD COM 03969F109 11,787 1,488,205 SH   SOLE   1,488,205 0 0
PREVAIL THERAPEUTICS ORD COM 74140Y101 31,582 2,392,556 SH   SOLE   838,235 0 0
UNITY BIOTECHNOLOGY ORD COM 91381U101 9,923 1,044,500 SH   SOLE   1,044,500 0 0
PROTHENA ORD COM G72800108 7,645 723,300 SH   SOLE   723,300 0 0
RUBIUS THERAPEUTICS ORD COM 78116T103 7,285 463,152 SH   SOLE   463,152 0 0
SURFACE ONCOLOGY ORD COM 86877M209 6,522 2,312,688 SH   SOLE   2,312,688 0 0
MERSANA THERAPEUTICS ORD COM 59045L106 5,639 1,392,231 SH   SOLE   1,392,231 0 0
CURIS ORD COM 231269200 5,547 2,982,208 SH   SOLE   2,982,208 0 0
AQUINOX PHARMACEUTICALS ORD COM 03842B101 5,347 2,265,880 SH   SOLE   2,265,880 0 0
CYCLERION THERAPEUTICS ORD COM 23255M105 8,888 776,206 SH   SOLE   438,572 0 0
RHYTHM PHARMACEUTICALS ORD COM 76243J105 4,910 223,167 SH   SOLE   223,167 0 0
SOLID BIOSCIENCES ORD COM 83422E105 4,755 827,000 SH   SOLE   827,000 0 0
NGM BIOPHARMACEUTICALS ORD COM 62921N105 4,639 316,900 SH   SOLE   316,900 0 0
KEZAR LIFE SCIENCES ORD COM 49372L100 4,497 583,293 SH   SOLE   583,293 0 0
ADURO BIOTECH ORD COM 00739L101 2,713 1,761,421 SH   SOLE   1,761,421 0 0
VERICEL ORD COM 92346J108 2,475 131,001 SH   SOLE   131,001 0 0
SYROS PHARMACEUTICALS ORD COM 87184Q107 2,301 248,480 SH   SOLE   248,480 0 0
GAMIDA CELL ORD COM M47364100 265 52,120 SH   SOLE   52,120 0 0
TCR2 THERAPEUTICS ORD COM 87808K106 231 16,114 SH   SOLE   16,114 0 0
ARGENX ADR REP ORD SPONSORED ADR 04016X101 82,281 581,165 SH   SOLE   581,165 0 0
REGULUS THERAPEUTICS COM 75915K200 1,389 1,111,110 SH   SOLE   1,111,110 0 0
GOSSAMER BIO INC ORD COM 38341P102 17,125 772,096 SH   SOLE   772,096 0 0