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RA CAPITAL MANAGEMENT, L.P.
> WVE
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Wave Life Sciences Ltd. | WVE | 17,202,009 | 0 | 62,615,313,000 | -57,798,750,000 | $3,640.00 |
| 12/31/2022 | Wave Life Sciences Ltd. | WVE | 17,202,009 | 0 | 120,414,063,000 | 120,351,964,000 | $7,000.00 |
| 09/30/2022 | Wave Life Sciences Ltd. | WVE | 17,202,009 | 0 | 62,099,000 | 6,192,000 | $3.61 |
| 06/30/2022 | Wave Life Sciences Ltd. | WVE | 17,202,009 | 9,426,802 | 55,907,000 | 40,357,000 | $3.25 |
| 03/31/2022 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 0 | 15,550,000 | -8,864,000 | $2.00 |
| 12/31/2021 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 0 | 24,414,000 | -13,685,000 | $3.14 |
| 09/30/2021 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 0 | 38,099,000 | -13,684,000 | $4.90 |
| 06/30/2021 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 0 | 51,783,000 | 8,164,000 | $6.66 |
| 03/31/2021 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 0 | 43,619,000 | -17,572,000 | $5.61 |
| 12/31/2020 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 0 | 61,191,000 | -4,821,000 | $7.87 |
| 09/30/2020 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 0 | 66,012,000 | -14,928,000 | $8.49 |
| 06/30/2020 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 0 | 80,940,000 | 8,086,000 | $10.41 |
| 03/31/2020 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 0 | 72,854,000 | 10,536,000 | $9.37 |
| 12/31/2019 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 0 | 62,318,000 | -97,307,000 | $8.01 |
| 09/30/2019 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 0 | 159,625,000 | -43,230,000 | $20.53 |
| 06/30/2019 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 0 | 202,855,000 | -99,212,000 | $26.09 |
| 03/31/2019 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 263,158 | 302,067,000 | -13,740,000 | $38.85 |
| 01/24/2019 | Wave Life Sciences Ltd. | WVE | 7,775,207 | 263,158 | 277,808,146 | -97,793,854 | $35.73 |
| 12/31/2018 | Wave Life Sciences Ltd. | WVE | 7,512,049 | 0 | 315,807,000 | -59,795,000 | $42.04 |
| 09/30/2018 | Wave Life Sciences Ltd. | WVE | 7,512,049 | 0 | 375,602,000 | 88,266,000 | $50.00 |
| 06/30/2018 | Wave Life Sciences Ltd. | WVE | 7,512,049 | 0 | 287,336,000 | -13,897,000 | $38.25 |
| 03/31/2018 | Wave Life Sciences Ltd. | WVE | 7,512,049 | 0 | 301,233,000 | 37,560,000 | $40.10 |
| 12/31/2017 | Wave Life Sciences Ltd. | WVE | 7,512,049 | 423,398 | 263,673,000 | 109,495,000 | $35.10 |
| 11/13/2017 | Wave Life Sciences Ltd. | WVE | 7,512,049 | 423,398 | 186,674,418 | 32,496,418 | $24.85 |
| 09/30/2017 | Wave Life Sciences Ltd. | WVE | 7,088,651 | 0 | 154,178,000 | 22,329,000 | $21.75 |
| 06/30/2017 | Wave Life Sciences Ltd. | WVE | 7,088,651 | 0 | 131,849,000 | -63,089,000 | $18.60 |
| 03/31/2017 | Wave Life Sciences Ltd. | WVE | 7,088,651 | 0 | 194,938,000 | 9,570,000 | $27.50 |
| 12/31/2016 | Wave Life Sciences Ltd. | WVE | 7,088,651 | 0 | 185,368,000 | -44,800,000 | $26.15 |
| 09/30/2016 | Wave Life Sciences Ltd. | WVE | 7,088,651 | 0 | 230,168,000 | 83,504,000 | $32.47 |
| 06/30/2016 | Wave Life Sciences Ltd. | WVE | 7,088,651 | 7,088,651 | 146,664,000 | 146,664,000 | $20.69 |
| 03/31/2016 | Wave Life Sciences Ltd. | WVE | 7,088,651 | 7,088,651 | 98,390,000 | 98,390,000 | $13.88 |
| 12/31/2015 | Wave Life Sciences Ltd. | WVE | 7,088,651 | 7,088,651 | 113,064,000 | 113,064,000 | $15.95 |
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