The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ABEONA THERAPEUTICS INC | COM | 00289Y107 | 5,543 | 1,142,857 | SH | SOLE | 1,142,857 | 0 | 0 | ||
| ACHILLION PHARMACEUTICALS INC | COM | 00448Q201 | 56,305 | 13,633,220 | SH | SOLE | 13,633,220 | 0 | 0 | ||
| AIMMUNE THERAPEUTICS INC | COM | 00900T107 | 13,858 | 677,663 | SH | SOLE | 677,663 | 0 | 0 | ||
| AKARI THERAPEUTICS PLC | SPONSORED ADR | 00972G108 | 714 | 101,439 | SH | SOLE | 101,439 | 0 | 0 | ||
| AQUINOX PHARMACEUTICALS INC | COM | 03842B101 | 36,190 | 2,191,977 | SH | SOLE | 2,191,977 | 0 | 0 | ||
| ARCA BIOPHARMA INC | COM PAR$.001 | 00211Y407 | 662 | 232,245 | SH | SOLE | 232,245 | 0 | 0 | ||
| ARDELYX INC | COM | 039697107 | 27,481 | 1,935,305 | SH | SOLE | 1,935,305 | 0 | 0 | ||
| ASCENDIS PHARMA A S | SPONSORED ADR | 04351P101 | 109,498 | 5,409,990 | SH | SOLE | 5,409,990 | 0 | 0 | ||
| AUDENTES THERAPEUTICS INC | COM | 05070R104 | 9,727 | 532,426 | SH | SOLE | 532,426 | 0 | 0 | ||
| AVEXIS INC | COM | 05366U100 | 90,248 | 1,890,796 | SH | SOLE | 1,890,796 | 0 | 0 | ||
| BEIGENE LTD | SPONSORED ADR | 07725L102 | 7,286 | 240,000 | SH | SOLE | 240,000 | 0 | 0 | ||
| BIOCRYST PHARMACEUTICALS | COM | 09058V103 | 18,925 | 2,989,795 | SH | SOLE | 2,989,795 | 0 | 0 | ||
| DICERNA PHARMACEUTICALS INC | COM | 253031108 | 6,994 | 2,428,571 | SH | SOLE | 2,428,571 | 0 | 0 | ||
| DIMENSION THERAPEUTICS INC | COM | 25433V105 | 4,038 | 928,199 | SH | SOLE | 928,199 | 0 | 0 | ||
| EIGER BIOPHARMACEUTICALS INC | COM | 28249U105 | 4,126 | 354,200 | SH | SOLE | 354,200 | 0 | 0 | ||
| FOAMIX PHARMACEUTICALS LTD | SHS | M46135105 | 20,204 | 1,820,138 | SH | SOLE | 1,820,138 | 0 | 0 | ||
| IDERA PHARMACEUTICALS INC | COM NEW | 45168K306 | 3,375 | 2,250,000 | SH | SOLE | 2,250,000 | 0 | 0 | ||
| KALVISTA PHARMACEUTICALS INC | COM | 483497103 | 4,179 | 591,070 | SH | SOLE | 591,070 | 0 | 0 | ||
| MEDICINES CO | COM | 584688105 | 2,712 | 79,899 | SH | SOLE | 79,899 | 0 | 0 | ||
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | 14,634 | 692,563 | SH | SOLE | 692,563 | 0 | 0 | ||
| RA PHARMACEUTICALS INC | COM | 74933V108 | 20,534 | 1,351,808 | SH | SOLE | 1,351,808 | 0 | 0 | ||
| STRONGBRIDGE BIOPHARMA PLC | SHS USD | G85347105 | 5,470 | 2,279,099 | SH | SOLE | 2,279,099 | 0 | 0 | ||
| TENAX THERAPEUTICS INC | COM | 88032L100 | 4,660 | 2,389,700 | SH | SOLE | 2,389,700 | 0 | 0 | ||
| TG THERAPEUTICS INC | COM | 88322Q108 | 4,670 | 1,004,314 | SH | SOLE | 1,004,314 | 0 | 0 | ||
| WAVE LIFE SCIENCES LTD | SHS | Y95308105 | 185,368 | 7,088,651 | SH | SOLE | 7,088,651 | 0 | 0 | ||
| ZOGENIX INC | COM NEW | 98978L204 | 29,783 | 2,451,237 | SH | SOLE | 2,451,237 | 0 | 0 | ||