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ORBIMED ADVISORS LLC
> TSVT
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | 2seventy bio, Inc. | TSVT | 2,391,628 | 0 | 24,203,275,000 | -191,331,000 | $10,120.00 |
| 03/31/2023 | 2seventy bio, Inc. | TSVT | 2,391,628 | 1,350,328 | 24,394,606,000 | 14,637,625,000 | $10,200.00 |
| 12/31/2022 | 2seventy bio, Inc. | TSVT | 1,041,300 | 0 | 9,756,981,000 | 9,741,830,000 | $9,370.00 |
| 09/30/2022 | 2seventy bio, Inc. | TSVT | 1,041,300 | 1,041,300 | 15,151,000 | 15,151,000 | $14.55 |
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