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JPMORGAN CHASE & CO
> AGIO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,492,975 | 1,294,462 | 70,601,052,000 | 43,071,052,000 | $28,320.00 |
| 03/31/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,198,513 | -288,082 | 27,530,000,000 | 27,487,959,000 | $22,970.13 |
| 09/30/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,486,595 | 76,859 | 42,041,000 | 10,788,000 | $28.28 |
| 06/30/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,409,736 | -1,865,656 | 31,253,000 | -64,092,000 | $22.17 |
| 03/31/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 3,275,392 | 174,982 | 95,345,000 | -6,566,000 | $29.11 |
| 12/31/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 3,100,410 | -1,142,575 | 101,911,000 | -93,903,000 | $32.87 |
| 09/30/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 4,242,985 | -919,326 | 195,814,000 | -88,681,000 | $46.15 |
| 06/30/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 5,162,311 | 1,794,683 | 284,495,000 | 110,591,000 | $55.11 |
| 03/31/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 3,367,628 | 1,279,865 | 173,904,000 | 83,441,000 | $51.64 |
| 12/31/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,087,763 | 460,364 | 90,463,000 | 34,480,000 | $43.33 |
| 09/30/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,627,399 | 34,160 | 55,983,000 | -29,223,000 | $34.40 |
| 06/30/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,593,239 | 274,154 | 85,206,000 | 38,404,000 | $53.48 |
| 03/31/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,319,085 | 366,349 | 46,802,000 | 1,310,000 | $35.48 |
| 12/31/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 952,736 | 194,810 | 45,492,000 | 20,935,000 | $47.75 |
| 09/30/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 757,926 | 5,161 | 24,557,000 | -12,833,000 | $32.40 |
| 06/30/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 752,765 | -241,999 | 37,390,000 | -29,697,000 | $49.67 |
| 03/31/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 994,764 | 99,450 | 67,087,000 | 25,804,000 | $67.44 |
| 12/31/2018 | AGIOS PHARMACEUTICALS, INC. | AGIO | 895,314 | 893,610 | 41,283,000 | 41,152,000 | $46.11 |
| 09/30/2018 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,704 | -1 | 131,000 | -13,000 | $76.88 |
| 06/30/2018 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,705 | 315 | 144,000 | 30,000 | $84.46 |
| 03/31/2018 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,390 | -170 | 114,000 | 25,000 | $82.01 |
| 12/31/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,560 | 90 | 89,000 | -6,000 | $57.05 |
| 09/30/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,470 | -1,191 | 95,000 | -42,000 | $64.63 |
| 06/30/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,661 | -12,360 | 137,000 | -741,000 | $51.48 |
| 03/31/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 15,021 | -307 | 878,000 | 239,000 | $58.45 |
| 12/31/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 15,328 | -61,767 | 639,000 | -3,432,000 | $41.69 |
| 09/30/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 77,095 | 77,095 | 4,071,000 | 4,071,000 | $52.80 |
| 06/30/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 30,882 | 30,882 | 1,294,000 | 1,294,000 | $41.90 |
| 03/31/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 5,877 | 5,877 | 239,000 | 239,000 | $40.67 |
| 03/31/2015 | AGIOS PHARMACEUTICALS, INC. | AGIO | 0 | -189,820 | 0 | -21,267,000 | |
| 12/31/2014 | AGIOS PHARMACEUTICALS, INC. | AGIO | 189,820 | 189,820 | 21,267,000 | 21,267,000 | $112.04 |
| 09/30/2014 | AGIOS PHARMACEUTICALS, INC. | AGIO | 142,970 | 142,970 | 8,771,000 | 8,771,000 | $61.35 |
| 06/30/2014 | AGIOS PHARMACEUTICALS, INC. | AGIO | 144,095 | 144,095 | 6,602,000 | 6,602,000 | $45.82 |
| 03/31/2014 | AGIOS PHARMACEUTICALS, INC. | AGIO | 156,325 | 156,325 | 6,120,000 | 6,120,000 | $39.15 |
| 12/31/2013 | AGIOS PHARMACEUTICALS, INC. | AGIO | 32,266 | 32,266 | 773,000 | 773,000 | $23.96 |
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