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JANUS HENDERSON GROUP PLC
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| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | AMICUS THERAPEUTICS, INC. | FOLD | 14,923,588 | 1,229,039 | 187,417,974,000 | 20,216,166,000 | $12,558.51 |
| 12/31/2022 | AMICUS THERAPEUTICS, INC. | FOLD | 13,694,549 | -1,081,566 | 167,201,808,000 | 167,047,541,000 | $12,209.37 |
| 09/30/2022 | AMICUS THERAPEUTICS, INC. | FOLD | 14,776,115 | -2,004,026 | 154,267,000 | -25,969,000 | $10.44 |
| 06/30/2022 | AMICUS THERAPEUTICS, INC. | FOLD | 16,780,141 | 1,157,528 | 180,236,000 | 32,279,000 | $10.74 |
| 03/31/2022 | AMICUS THERAPEUTICS, INC. | FOLD | 15,622,613 | 5,764,732 | 147,957,000 | 34,079,000 | $9.47 |
| 12/31/2021 | AMICUS THERAPEUTICS, INC. | FOLD | 9,857,881 | 2,803,673 | 113,878,000 | 46,500,000 | $11.55 |
| 09/30/2021 | AMICUS THERAPEUTICS, INC. | FOLD | 7,054,208 | 2,065,621 | 67,378,000 | 19,286,000 | $9.55 |
| 06/30/2021 | AMICUS THERAPEUTICS, INC. | FOLD | 4,988,587 | -3,995,468 | 48,092,000 | -40,670,000 | $9.64 |
| 03/31/2021 | AMICUS THERAPEUTICS, INC. | FOLD | 8,984,055 | -2,263,153 | 88,762,000 | -170,939,000 | $9.88 |
| 12/31/2020 | AMICUS THERAPEUTICS, INC. | FOLD | 11,247,208 | -2,859,051 | 259,701,000 | 60,520,000 | $23.09 |
| 09/30/2020 | AMICUS THERAPEUTICS, INC. | FOLD | 14,106,259 | 2,312,500 | 199,181,000 | 21,332,000 | $14.12 |
| 06/30/2020 | AMICUS THERAPEUTICS, INC. | FOLD | 11,793,759 | 167,835 | 177,849,000 | 70,426,000 | $15.08 |
| 03/31/2020 | AMICUS THERAPEUTICS, INC. | FOLD | 11,625,924 | 867,308 | 107,423,000 | 2,634,000 | $9.24 |
| 12/31/2019 | AMICUS THERAPEUTICS, INC. | FOLD | 10,758,616 | -187,619 | 104,789,000 | 17,000,000 | $9.74 |
| 09/30/2019 | AMICUS THERAPEUTICS, INC. | FOLD | 10,946,235 | 10,946,235 | 87,789,000 | 87,789,000 | $8.02 |
| 06/30/2019 | AMICUS THERAPEUTICS, INC. | FOLD | 0 | -11,056,142 | 0 | -150,363,000 | |
| 03/31/2019 | AMICUS THERAPEUTICS, INC. | FOLD | 11,056,142 | -17,442 | 150,363,000 | 44,278,000 | $13.60 |
| 02/12/2019 | AMICUS THERAPEUTICS, INC. | FOLD | 11,073,584 | 0 | 124,024,141 | 17,939,141 | $11.20 |
| 12/31/2018 | AMICUS THERAPEUTICS, INC. | FOLD | 11,073,584 | 2,267,225 | 106,085,000 | -384,000 | $9.58 |
| 09/30/2018 | AMICUS THERAPEUTICS, INC. | FOLD | 8,806,359 | 627,972 | 106,469,000 | -21,277,000 | $12.09 |
| 06/30/2018 | AMICUS THERAPEUTICS, INC. | FOLD | 8,178,387 | -367,952 | 127,746,000 | -791,000 | $15.62 |
| 03/31/2018 | AMICUS THERAPEUTICS, INC. | FOLD | 8,546,339 | 629,638 | 128,537,000 | 14,616,000 | $15.04 |
| 12/31/2017 | AMICUS THERAPEUTICS, INC. | FOLD | 7,916,701 | 482,387 | 113,921,000 | 1,812,000 | $14.39 |
| 09/30/2017 | AMICUS THERAPEUTICS, INC. | FOLD | 7,434,314 | 407,304 | 112,109,000 | 112,038,238 | $15.08 |
| 06/30/2017 | AMICUS THERAPEUTICS, INC. | FOLD | 7,027,010 | 7,027,010 | 70,762 | 70,762 | $0.01 |
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