Spero Therapeutics, Inc. (SPRO) [Rocket]

Ownership

Spero Therapeutics, Inc. (SPRO)

Portfolio as of:

Name	Shares	Change	Value	% Port	% OS	Hist	Date
Anson Funds Management LP	3,444,862	100,000	4,995,050,000	0.83	6.55	Hist	06/30/2023
VANGUARD GROUP INC	1,526,474	472,751	2,213,387,000	0.00	2.90	Hist	06/30/2023
Atlas Venture Associates IX, LLC	1,353,303	-23,665	1,962,289,000	10.74	2.57	Hist	06/30/2023
Atlas Venture Life Science Advisors, LLC	1,013,438	-17,722	1,469,485,000	0.18	1.93	Hist	06/30/2023
Alphabet Inc.	889,979	0	1,290,470,000	0.07	1.72	Hist	03/31/2023
Murchinson Ltd.	762,700	-42,921	1,105,915,000	0.14	1.45	Hist	06/30/2023
Rock Springs Capital Management LP	669,533	0	970,823,000	0.02	1.27	Hist	06/30/2023
BlackRock Inc.	523,804	33,991	759,515,000	0.00	1.00	Hist	06/30/2023
Novo Holdings A/S	468,902	0	679,908,000	0.05	0.89	Hist	06/30/2023
AMERIPRISE FINANCIAL INC	467,960	467,960	678,543,000	0.00	0.89	Hist	06/30/2023
GEODE CAPITAL MANAGEMENT, LLC	390,805	52,949	566,667,000	0.00	0.74	Hist	06/30/2023
AWM Investment Company, Inc.	383,400	-917,000	555,930,000	0.08	0.73	Hist	06/30/2023
MILLENNIUM MANAGEMENT LLC	373,850	-502,548	542,082,000	0.00	0.71	Hist	06/30/2023
OUP Management Co., LLC	249,070	0	361,152,000	0.62	0.47	Hist	06/30/2023
DAFNA Capital Management LLC	125,000	0	181,250,000	0.05	0.24	Hist	06/30/2023
STATE STREET CORP	110,711	0	160,531,000	0.00	0.21	Hist	06/30/2023
BRIDGEWAY CAPITAL MANAGEMENT, LLC	109,800	0	159,210,000	0.00	0.21	Hist	06/30/2023
XTX Topco Ltd	106,384	-240,350	154,257,000	0.03	0.20	Hist	06/30/2023
GROUP ONE TRADING, L.P.	91,970	4,866	133,357,000	0.00	0.17	Hist	06/30/2023
NORTHERN TRUST CORP	88,745	2,489	128,680,000	0.00	0.17	Hist	06/30/2023
TWO SIGMA INVESTMENTS, LP	84,535	52,435	122,576,000	0.00	0.16	Hist	06/30/2023
Squarepoint Ops LLC	78,063	78,063	113,191,000	0.00	0.15	Hist	06/30/2023
BIOTECHNOLOGY VALUE FUND L P	3,411,520	643,242	54,618,435			Hist	12/31/2021
UBS Group AG	27,071	-14,452	39,253,000	0.00	0.05	Hist	06/30/2023
PRUDENTIAL FINANCIAL INC	24,400	24,400	35,380,000	0.00	0.05	Hist	06/30/2023
ROYCE & ASSOCIATES LP	22,851	22,851	33,134,000	0.00	0.04	Hist	06/30/2023
MACKENZIE FINANCIAL CORP	17,198	17,198	25,281,000	0.00	0.03	Hist	06/30/2023
Atlas Venture Fund IX, L.P.	1,376,968	0	22,045,258			Hist	12/31/2021
CITADEL ADVISORS LLC	14,956	14,956	21,686,000	0.00	0.03	Hist	06/30/2023
SENTINEL PENSION ADVISORS INC	12,000	0	20,760,000	0.01	0.02	Hist	12/31/2022
BANK OF AMERICA CORP /DE/	13,237	-5,180	19,193,000	0.00	0.03	Hist	06/30/2023
DIMENSIONAL FUND ADVISORS LP	11,753	0	17,042,000	0.00	0.02	Hist	06/30/2023
Texas Yale Capital Corp.	10,000	0	14,500,000	0.00	0.02	Hist	06/30/2023
MORGAN STANLEY	9,530	-7,547	13,819,000	0.00	0.02	Hist	06/30/2023
Russell Investments Group, Ltd.	6,400	0	9,280,000	0.00	0.01	Hist	06/30/2023
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