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Amylyx Pharmaceuticals, Inc.

Portfolio as of:
NameSharesChangeValue% Port% OSHistDate
VANGUARD GROUP INC 4,925,8921,411,536106,251,491,0000.007.33 Hist 06/30/2023
PERCEPTIVE ADVISORS LLC 4,873,919-1,214,414105,130,433,000   Hist 06/30/2023
BlackRock Inc. 3,505,285-109,63375,608,999,0000.005.22 Hist 06/30/2023
VIKING GLOBAL INVESTORS LP 2,962,555-1,672,05163,902,311,0000.264.41 Hist 06/30/2023
MARSHALL WACE, LLP 1,980,1801,980,18042,712,483,0000.082.95 Hist 06/30/2023
MILLENNIUM MANAGEMENT LLC 1,921,6311,062,21641,449,581,0000.022.86 Hist 06/30/2023
GOLDMAN SACHS GROUP INC 1,366,172986,77340,083,487,0000.012.05 Hist 03/31/2023
D. E. Shaw & Co., Inc. 1,590,044206,31234,297,249,0000.042.37 Hist 06/30/2023
Rock Springs Capital Management LP 1,544,61691,80033,317,367,0000.792.30 Hist 06/30/2023
FEDERATED HERMES, INC. 1,529,000-317,11732,980,530,0000.082.28 Hist 06/30/2023
EMERALD ADVISERS, LLC 972,835972,83528,542,979,0001.371.46 Hist 03/31/2023
BALYASNY ASSET MANAGEMENT L.P. 1,173,853753,01225,320,009,0000.061.75 Hist 06/30/2023
STATE STREET CORP 1,157,69982,08724,971,567,0000.001.72 Hist 06/30/2023
Stonepine Capital Management, LLC 1,121,0281,121,02824,180,574,0009.081.67 Hist 06/30/2023
EVENTIDE ASSET MANAGEMENT, LLC 1,116,837658,78324,090,174,0000.411.66 Hist 06/30/2023
MORGAN STANLEY 1,051,846567,37722,688,319,0000.001.57 Hist 06/30/2023
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) 1,050,198-1,642,80222,652,771,0000.481.56 Hist 06/30/2023
GREAT POINT PARTNERS LLC 968,795778,79520,896,908,0004.091.44 Hist 06/30/2023
GEODE CAPITAL MANAGEMENT, LLC 937,99747,01520,232,602,0000.001.40 Hist 06/30/2023
VOYA INVESTMENT MANAGEMENT LLC 937,540318,51020,222,738,0000.021.40 Hist 06/30/2023
Avidity Partners Management LP 901,4001,40019,443,198,0000.681.34 Hist 06/30/2023
Woodline Partners LP 899,300465,10019,397,901,0000.231.34 Hist 06/30/2023
Alpha Wave Global, LP 853,262-77,07518,404,861,00012.061.27 Hist 06/30/2023
CITADEL ADVISORS LLC 813,325756,56817,543,420,0000.001.21 Hist 06/30/2023
ADAGE CAPITAL PARTNERS GP, L.L.C. 768,200-239,13616,570,074,0000.041.14 Hist 06/30/2023
EMERALD MUTUAL FUND ADVISERS TRUST 680,035-109,55614,668,355,0000.801.01 Hist 06/30/2023
PICTET ASSET MANAGEMENT SA 601,646-832,20012,977,504,0000.020.90 Hist 06/30/2023
Nuveen Asset Management, LLC 553,074-58,85811,929,806,000   Hist 06/30/2023
Ghost Tree Capital, LLC 550,00075,00011,863,500,0003.920.82 Hist 06/30/2023
NORTHERN TRUST CORP 485,41821,53810,470,466,0000.000.72 Hist 06/30/2023
JANE STREET GROUP, LLC 473,393336,83610,211,087,0000.000.70 Hist 06/30/2023
GMT CAPITAL CORP 461,000461,0009,943,770,0000.380.69 Hist 06/30/2023
FMR LLC 448,982441,7529,684,542,0000.000.67 Hist 06/30/2023
SECTORAL ASSET MANAGEMENT INC 387,310144,9108,354,277,0001.390.58 Hist 06/30/2023
Alyeska Investment Group, L.P. 320,15768,7506,905,786,0000.050.48 Hist 06/30/2023
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