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Soleus Capital Management, L.P.
> LYRA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Lyra Therapeutics, Inc. | LYRA | 592,417 | 0 | 2,434,834,000 | 1,244,076,000 | $4,110.00 |
| 03/31/2023 | Lyra Therapeutics, Inc. | LYRA | 592,417 | 0 | 1,190,758,000 | -669,431,000 | $2,010.00 |
| 12/31/2022 | Lyra Therapeutics, Inc. | LYRA | 592,417 | 0 | 1,860,189,000 | 1,857,221,000 | $3,140.00 |
| 09/30/2022 | Lyra Therapeutics, Inc. | LYRA | 592,417 | 0 | 2,968,000 | -379,000 | $5.01 |
| 06/30/2022 | Lyra Therapeutics, Inc. | LYRA | 592,417 | 592,417 | 3,347,000 | 3,347,000 | $5.65 |
| 03/31/2022 | Lyra Therapeutics, Inc. | LYRA | 0 | -10,000 | 0 | -44,000 | |
| 12/31/2021 | Lyra Therapeutics, Inc. | LYRA | 10,000 | -205,576 | 44,000 | -1,923,000 | $4.40 |
| 09/30/2021 | Lyra Therapeutics, Inc. | LYRA | 215,576 | 32,500 | 1,967,000 | 497,000 | $9.12 |
| 06/30/2021 | Lyra Therapeutics, Inc. | LYRA | 183,076 | -273,062 | 1,470,000 | -3,729,000 | $8.03 |
| 12/31/2020 | Lyra Therapeutics, Inc. | LYRA | 456,138 | 345,468 | 5,199,000 | 3,962,000 | $11.40 |
| 09/30/2020 | Lyra Therapeutics, Inc. | LYRA | 110,670 | 50,000 | 1,237,000 | 550,000 | $11.18 |
| 06/30/2020 | Lyra Therapeutics, Inc. | LYRA | 60,670 | 60,670 | 687,000 | 687,000 | $11.32 |
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