The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC COM 00287Y109 2,301 21,477 SH   SOLE   21,477 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 1,474 135,992 SH   SOLE   135,992 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 2,959 18,938 SH   SOLE   18,938 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 517 41,064 SH   SOLE   41,064 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 3,214 64,284 SH   SOLE   64,284 0 0
AXOGEN INC COM 05463X106 605 33,813 SH   SOLE   33,813 0 0
BIOATLA INC COM 09077B104 108,130 3,179,362 SH   SOLE   3,179,362 0 0
BIOGEN INC COM 09062X103 955 3,899 SH   SOLE   3,899 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 657 7,661 SH   SOLE   7,661 0 0
C4 THERAPEUTICS INC COM STK 12529R107 8,897 268,548 SH   SOLE   268,548 0 0
CARDIFF ONCOLOGY INC COM 14147L108 1,024 56,909 SH   SOLE   56,909 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101 2,036 42,743 SH   SOLE   42,743 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 1,657 10,825 SH   SOLE   10,825 0 0
DARIOHEALTH CORP COM NEW 23725P209 5,739 401,606 SH   SOLE   401,606 0 0
DEXCOM INC COM 252131107 3,018 8,165 SH   SOLE   8,165 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 2,282 185,719 SH   SOLE   185,719 0 0
ESSA PHARMA INC COM NEW 29668H708 28,342 2,375,681 SH   SOLE   2,375,681 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108 2,519 66,921 SH   SOLE   66,921 0 0
EXELIXIS INC COM 30161Q104 7,844 390,847 SH   SOLE   390,847 0 0
FATE THERAPEUTICS INC COM 31189P102 621 6,830 SH   SOLE   6,830 0 0
GALECTO INC COM 36322Q107 18,923 1,512,648 SH   SOLE   1,512,648 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 2,477 2,750,000 PRN   SOLE   2,750,000 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 926 12,655 SH   SOLE   12,655 0 0
INHIBRX INC COM 45720L107 7,049 213,807 SH   SOLE   213,807 0 0
INVITAE CORP COM 46185L103 10,233 244,760 SH   SOLE   244,760 0 0
IONIS PHARMACEUTICALS INC NOTE 0.125%12/1 462222AB6 8,675 8,500,000 PRN   SOLE   8,500,000 0 0
IRADIMED CORP COM 46266A109 6,931 303,998 SH   SOLE   303,998 0 0
ITAMAR MED LTD SPONSORED ADS 465437101 2,791 140,524 SH   SOLE   140,524 0 0
IVERIC BIO INC COM 46583P102 11,037 1,597,279 SH   SOLE   1,597,279 0 0
KADMON HLDGS INC COM 48283N106 1,396 336,442 SH   SOLE   336,442 0 0
KRYSTAL BIOTECH INC COM 501147102 625 10,423 SH   SOLE   10,423 0 0
KYMERA THERAPEUTICS INC COM 501575104 813 13,116 SH   SOLE   13,116 0 0
LANTHEUS HLDGS INC COM 516544103 10,011 742,085 SH   SOLE   742,085 0 0
LYRA THERAPEUTICS INC COM 55234L105 5,199 456,138 SH   SOLE   456,138 0 0
MEDICENNA THERAPEUTICS CORP COM 58490H107 874 186,799 SH   SOLE   186,799 0 0
MERCK & CO. INC COM 58933Y105 2,324 28,406 SH   SOLE   28,406 0 0
MERSANA THERAPEUTICS INC COM 59045L106 5,504 206,844 SH   SOLE   206,844 0 0
MIRAGEN THERAPEUTICS INC COM NEW 60463E202 1,335 81,185 SH   SOLE   81,185 0 0
MIRATI THERAPEUTICS INC COM 60468T105 1,722 7,838 SH   SOLE   7,838 0 0
MISONIX INC COM 604871103 3,767 301,333 SH   SOLE   301,333 0 0
NATERA INC COM 632307104 7,383 74,189 SH   SOLE   74,189 0 0
NEOGENOMICS INC COM NEW 64049M209 2,474 45,951 SH   SOLE   45,951 0 0
NEVRO CORP COM 64157F103 1,660 9,589 SH   SOLE   9,589 0 0
NOVOCURE LTD ORD SHS G6674U108 4,326 24,999 SH   SOLE   24,999 0 0
OAK STR HEALTH INC COM 67181A107 1,689 27,612 SH   SOLE   27,612 0 0
OAKTREE ACQUISITION CORP *W EXP 99/99/999 G67145113 358 91,793 SH   SOLE   91,793 0 0
OAKTREE ACQUISITION CORP SHS CL A G67145105 4,111 281,565 SH   SOLE   281,565 0 0
ONCORUS INC COM 68236R103 1,824 56,422 SH   SOLE   56,422 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 1,250 500,000 SH   SOLE   500,000 0 0
PROTARA THERAPEUTICS INC COM STK 74365U107 390 16,093 SH   SOLE   16,093 0 0
PROVENTION BIO INC COM 74374N102 1,795 105,941 SH   SOLE   105,941 0 0
RAFAEL HLDGS INC COM CL B 75062E106 2,442 104,737 SH   SOLE   104,737 0 0
REVANCE THERAPEUTICS INC COM 761330109 882 31,136 SH   SOLE   31,136 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 1,188 24,484 SH   SOLE   24,484 0 0
SILVERBACK THERAPEUTICS INC COM 82835W108 4,997 107,826 SH   SOLE   107,826 0 0
SPDR SER TR S&P BIOTECH 78464A870 397,704 2,825,000 SH Put SOLE   2,825,000 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 261 3,300 SH   SOLE   3,300 0 0
SURMODICS INC COM 868873100 4,046 92,975 SH   SOLE   92,975 0 0
TCR2 THERAPEUTICS INC COM 87808K106 6,182 199,867 SH   SOLE   199,867 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 1,527 103,819 SH   SOLE   103,819 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 2,317 19,013 SH   SOLE   19,013 0 0
VERICEL CORP COM 92346J108 7,305 236,589 SH   SOLE   236,589 0 0
VESPER HEALTHCARE ACQSTN COR COM CL A 92538T104 4,711 416,551 SH   SOLE   416,551 0 0
XENON PHARMACEUTICALS INC COM 98420N105 8,584 558,117 SH   SOLE   558,117 0 0
ZYMEWORKS INC COM 98985W102 1,070 22,631 SH   SOLE   22,631 0 0