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DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)
> BSMD
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2010 | BIOSPHERE MEDICAL INC | BSMD | 1,766,526 | 0 | 7,631,000 | 2,950,000 | $4.32 |
| 03/31/2010 | BIOSPHERE MEDICAL INC | BSMD | 1,766,526 | 668,465 | 4,681,000 | 1,672,000 | $2.65 |
| 12/31/2009 | BIOSPHERE MEDICAL INC | BSMD | 1,098,061 | 0 | 3,009,000 | -735,000 | $2.74 |
| 09/30/2009 | BIOSPHERE MEDICAL INC | BSMD | 1,098,061 | -79,324 | 3,744,000 | 930,000 | $3.41 |
| 06/30/2009 | BIOSPHERE MEDICAL INC | BSMD | 1,177,385 | 0 | 2,814,000 | 459,000 | $2.39 |
| 03/31/2009 | BIOSPHERE MEDICAL INC | BSMD | 1,177,385 | 54,472 | 2,355,000 | 188,000 | $2.00 |
| 12/31/2008 | BIOSPHERE MEDICAL INC | BSMD | 1,122,913 | 127,573 | 2,167,000 | -1,341,000 | $1.93 |
| 09/30/2008 | BIOSPHERE MEDICAL INC | BSMD | 995,340 | 995,340 | 3,508,000 | 3,508,000 | $3.52 |
| 06/30/2008 | BIOSPHERE MEDICAL INC | BSMD | 662,893 | 662,893 | 2,285,000 | 2,285,000 | $3.45 |
| 03/31/2008 | BIOSPHERE MEDICAL INC | BSMD | 559,754 | 559,754 | 2,569,000 | 2,569,000 | $4.59 |
| 12/31/2007 | BIOSPHERE MEDICAL INC | BSMD | 228,433 | 228,433 | 1,172,000 | 1,172,000 | $5.13 |
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