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STATE STREET CORP
> AVGN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2009 | AVIGEN INC \DE | AVGN | 17,802 | 0 | 23,000 | -4,000 | $1.29 |
| 09/30/2009 | AVIGEN INC \DE | AVGN | 17,802 | 0 | 27,000 | 4,000 | $1.52 |
| 06/30/2009 | AVIGEN INC \DE | AVGN | 17,802 | 0 | 23,000 | 1,000 | $1.29 |
| 03/31/2009 | AVIGEN INC \DE | AVGN | 17,802 | -8,400 | 22,000 | 2,000 | $1.24 |
| 12/31/2008 | AVIGEN INC \DE | AVGN | 26,202 | 26,202 | 20,000 | 20,000 | $0.76 |
| 09/30/2008 | AVIGEN INC \DE | AVGN | 0 | -26,202 | 0 | -76,000 | |
| 06/30/2008 | AVIGEN INC \DE | AVGN | 26,202 | -5,600 | 76,000 | -13,000 | $2.90 |
| 03/31/2008 | AVIGEN INC \DE | AVGN | 31,802 | 0 | 89,000 | -46,000 | $2.80 |
| 12/31/2007 | AVIGEN INC \DE | AVGN | 31,802 | 4,690 | 135,000 | -11,000 | $4.25 |
| 09/30/2007 | AVIGEN INC \DE | AVGN | 27,112 | 0 | 146,000 | -21,000 | $5.39 |
| 06/30/2007 | AVIGEN INC \DE | AVGN | 27,112 | 0 | 167,000 | -9,000 | $6.16 |
| 03/31/2007 | AVIGEN INC \DE | AVGN | 27,112 | 27,112 | 176,000 | 176,000 | $6.49 |
| 12/31/2006 | AVIGEN INC \DE | AVGN | 0 | -18,712 | 0 | -97,000 | |
| 09/30/2006 | AVIGEN INC \DE | AVGN | 18,712 | 0 | 97,000 | 0 | $5.18 |
| 06/30/2006 | AVIGEN INC \DE | AVGN | 18,712 | 0 | 97,000 | 0 | $5.18 |
| 03/31/2006 | AVIGEN INC \DE | AVGN | 18,712 | 0 | 97,000 | 40,000 | $5.18 |
| 12/31/2005 | AVIGEN INC \DE | AVGN | 18,712 | -9,100 | 57,000 | -20,000 | $3.05 |
| 09/30/2005 | AVIGEN INC \DE | AVGN | 27,812 | 5,600 | 77,000 | 9,000 | $2.77 |
| 06/30/2005 | AVIGEN INC \DE | AVGN | 22,212 | 0 | 68,000 | 6,000 | $3.06 |
| 03/31/2005 | AVIGEN INC \DE | AVGN | 22,212 | 0 | 62,000 | -10,000 | $2.79 |
| 12/31/2004 | AVIGEN INC \DE | AVGN | 22,212 | 0 | 72,000 | -11,000 | $3.24 |
| 09/30/2004 | AVIGEN INC \DE | AVGN | 22,212 | 0 | 83,000 | 8,000 | $3.74 |
| 06/30/2004 | AVIGEN INC \DE | AVGN | 22,212 | -49,036 | 75,000 | -189,330 | $3.38 |
| 06/30/2003 | AVIGEN INC \DE | AVGN | 71,248 | -175,448 | 264,330 | -456,022 | $3.71 |
| 03/31/2003 | AVIGEN INC \DE | AVGN | 246,696 | 16,852 | 720,352 | -592,057 | $2.92 |
| 12/31/2002 | AVIGEN INC \DE | AVGN | 229,844 | -395 | 1,312,409 | -513,386 | $5.71 |
| 09/30/2002 | AVIGEN INC \DE | AVGN | 230,239 | 230,239 | 1,825,795 | 1,825,795 | $7.93 |
| 06/30/2002 | AVIGEN INC \DE | AVGN | 0 | -176,046 | 0 | -1,954,110 | |
| 03/31/2002 | AVIGEN INC \DE | AVGN | 176,046 | 4,250 | 1,954,110 | -23,261 | $11.10 |
| 12/31/2001 | AVIGEN INC \DE | AVGN | 171,796 | 12,700 | 1,977,371 | -203,835 | $11.51 |
| 09/30/2001 | AVIGEN INC \DE | AVGN | 159,096 | 28,174 | 2,181,206 | -633,617 | $13.71 |
| 06/30/2001 | AVIGEN INC \DE | AVGN | 130,922 | 5,498 | 2,814,823 | 1,286,281 | $21.50 |
| 05/04/2001 | AVIGEN INC \DE | AVGN | 125,424 | -4,100 | 1,528,542 | -1,159,081 | $12.19 |
| 12/31/2000 | AVIGEN INC \DE | AVGN | 129,524 | 33,988 | 2,687,623 | -1,109,933 | $20.75 |
| 09/30/2000 | AVIGEN INC \DE | AVGN | 95,536 | 95,536 | 3,797,556 | 3,797,556 | $39.75 |
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