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TEKLA HEALTHCARE INVESTORS
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2004 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -189,700 | 0 | -1,786,974 | |
| 03/31/2004 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 189,700 | 189,700 | 1,786,974 | 1,786,974 | $9.42 |
| 12/31/2003 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 189,700 | 189,700 | 1,940,631 | 1,940,631 | $10.23 |
| 09/30/2003 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 189,700 | 189,700 | 2,333,310 | 2,333,310 | $12.30 |
| 06/30/2003 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 189,700 | 189,700 | 2,769,620 | 2,769,620 | $14.60 |
| 03/31/2003 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 189,700 | 189,700 | 2,109,464 | 2,109,464 | $11.12 |
| 12/31/2002 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 189,700 | 189,700 | 3,006,745 | 3,006,745 | $15.85 |
| 09/30/2002 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 189,700 | 189,700 | 3,507,553 | 3,507,553 | $18.49 |
| 06/30/2002 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 189,700 | 189,700 | 3,088,316 | 3,088,316 | $16.28 |
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