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TEKLA HEALTHCARE INVESTORS
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| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2004 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 727,665 | 727,665 | 17,369,000 | 17,369,000 | $23.87 |
| 03/31/2004 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 727,665 | 727,665 | 19,530,529 | 19,530,529 | $26.84 |
| 12/31/2003 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 727,665 | 727,665 | 16,743,571 | 16,743,571 | $23.01 |
| 09/30/2003 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 706,665 | 706,665 | 14,168,633 | 14,168,633 | $20.05 |
| 06/30/2003 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 666,665 | 666,665 | 10,713,307 | 10,713,307 | $16.07 |
| 03/31/2003 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 666,665 | 666,665 | 8,959,977 | 8,959,977 | $13.44 |
| 12/31/2002 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 666,665 | 666,665 | 7,773,313 | 7,773,313 | $11.66 |
| 09/30/2002 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 666,665 | 666,665 | 8,253,313 | 8,253,313 | $12.38 |
| 06/30/2002 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 666,665 | 666,665 | 8,333,313 | 8,333,313 | $12.50 |
| 03/31/2002 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 666,665 | 666,665 | 8,079,979 | 8,079,979 | $12.12 |
| 12/31/2001 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 666,665 | 666,665 | 8,999,978 | 8,999,978 | $13.50 |
| 09/30/2001 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 666,665 | 666,665 | 4,333,323 | 4,333,323 | $6.50 |
| 06/30/2001 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 666,665 | 666,665 | 6,566,650 | 6,566,650 | $9.85 |
| 03/31/2001 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 666,666 | 666,666 | 3,458,324 | 3,458,324 | $5.19 |
| 12/31/2000 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 666,666 | 666,666 | 3,313,330 | 3,313,330 | $4.97 |
| 09/30/2000 | MABVAX THERAPEUTICS HOLDINGS, INC. | TELK | 666,666 | 666,666 | 4,559,996 | 4,559,996 | $6.84 |
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