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TEKLA HEALTHCARE INVESTORS
> AMGN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2004 | AMGEN INC | AMGN | 196,000 | 196,000 | 10,696,000 | 10,696,000 | $54.57 |
| 03/31/2004 | AMGEN INC | AMGN | 196,000 | 196,000 | 11,401,320 | 11,401,320 | $58.17 |
| 12/31/2003 | AMGEN INC | AMGN | 135,000 | 135,000 | 8,343,000 | 8,343,000 | $61.80 |
| 09/30/2003 | AMGEN INC | AMGN | 135,000 | 135,000 | 8,716,950 | 8,716,950 | $64.57 |
| 06/30/2003 | AMGEN INC | AMGN | 135,000 | 135,000 | 8,969,400 | 8,969,400 | $66.44 |
| 03/31/2001 | AMGEN INC | AMGN | 0 | -150,000 | 0 | -9,590,625 | |
| 12/31/2000 | AMGEN INC | AMGN | 150,000 | 150,000 | 9,590,625 | 9,590,625 | $63.94 |
| 09/30/2000 | AMGEN INC | AMGN | 150,000 | 150,000 | 10,474,219 | 10,474,219 | $69.83 |
| 06/30/2000 | AMGEN INC | AMGN | 150,000 | 150,000 | 10,537,500 | 10,537,500 | $70.25 |
| 03/31/2000 | AMGEN INC | AMGN | 150,000 | 150,000 | 9,206,250 | 9,206,250 | $61.38 |
| 12/31/1999 | AMGEN INC | AMGN | 150,000 | 150,000 | 9,009,375 | 9,009,375 | $60.06 |
| 09/30/1999 | AMGEN INC | AMGN | 75,000 | 75,000 | 6,112,500 | 6,112,500 | $81.50 |
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