| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/29/2023 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Exercise | Restricted Share Units | 5k | $0.00 | $0 | | 06/29/2023 |
| 06/06/2023 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Grant | Share Option | 26.2k | $15.19 | $398.5k | | 06/06/2023 |
| 06/06/2023 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Grant | Restricted Share Units | 4.4k | $0.00 | $0 | | 06/06/2023 |
| 01/18/2023 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Grant | Employee Stock Option (Right to Buy) | 850k | $3.13 | $2.7M | | 01/18/2023 |
| 11/29/2022 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Sale | Class A Common Share | 22k | $16.15 | $354.6k | | 11/29/2022 |
| 11/29/2022 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Exercise | Share Option | 22k | $1.59 | $34.9k | | 11/29/2022 |
| 10/13/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Payment of Exercise | Common Stock | 5.2k | $3.76 | $19.6k | | 10/13/2022 |
| 10/13/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Exercise | Restricted Stock Units | 3.6k | $0.00 | $0 | | 10/13/2022 |
| 10/13/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Exercise | Restricted Stock Units | 16.1k | $0.00 | $0 | | 10/13/2022 |
| 07/13/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Payment of Exercise | Common Stock | 5.2k | $3.01 | $15.7k | | 07/13/2022 |
| 07/13/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Exercise | Restricted Stock Units | 3.6k | $0.00 | $0 | | 07/13/2022 |
| 07/13/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Exercise | Restricted Stock Units | 16.1k | $0.00 | $0 | | 07/13/2022 |
| 06/29/2022 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Grant | Restricted Share Units | 5k | $0.00 | $0 | | 06/29/2022 |
| 06/29/2022 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Grant | Share Option | 30k | $9.88 | $296.4k | | 06/29/2022 |
| 04/29/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Other (acquisition) | Common Stock | 1.5k | $3.84 | $5.8k | | 07/13/2022 |
| 04/13/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Exercise | Restricted Stock Units | 16.1k | $0.00 | $0 | | 04/13/2022 |
| 04/13/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Exercise | Restricted Stock Units | 3.6k | $0.00 | $0 | | 04/13/2022 |
| 04/13/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Payment of Exercise | Common Stock | 5.2k | $6.07 | $31.7k | | 04/13/2022 |
| 01/13/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Payment of Exercise | Common Stock | 5.2k | $8.30 | $43.3k | | 01/13/2022 |
| 01/13/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Exercise | Restricted Stock Units | 3.6k | $0.00 | $0 | | 01/13/2022 |
| 01/13/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Exercise | Restricted Stock Units | 16.1k | $0.00 | $0 | | 01/13/2022 |
| 10/13/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Grant | Restricted Stock Units | 195.4k | $0.00 | $0 | | 10/13/2021 |
| 10/13/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Grant | Employee Stock Option (Right to Buy) | 390.8k | $10.55 | $4.1M | | 10/13/2021 |
| 10/13/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Exercise | Restricted Stock Units | 3.6k | $0.00 | $0 | | 10/13/2021 |
| 10/13/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Payment of Exercise | Common Stock | 963 | $10.55 | $10.2k | | 10/13/2021 |
| 07/13/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Payment of Exercise | Common Stock | 963 | $13.48 | $13k | | 07/13/2021 |
| 07/13/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Exercise | Restricted Stock Units | 3.6k | $0.00 | $0 | | 07/13/2021 |
| 06/29/2021 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Grant | Share Option | 33.2k | $14.33 | $476.3k | | 06/29/2021 |
| 04/30/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Other (acquisition) | Common Stock | 1.5k | $13.90 | $21.2k | | 07/13/2021 |
| 04/13/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Payment of Exercise | Common Stock | 963 | $16.66 | $16k | | 06/20/2015 |
| 04/13/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Exercise | Restricted Stock Units | 3.6k | $0.00 | $0 | | 06/20/2015 |
| 01/13/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Payment of Exercise | Common Stock | 963 | $18.16 | $17.5k | | 01/13/2021 |
| 01/13/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Exercise | Restricted Stock Units | 3.6k | $0.00 | $0 | | 01/13/2021 |
| 10/13/2020 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Grant | Employee Stock Option (Right to Buy) | 350k | $15.72 | $5.5M | | 10/13/2020 |
| 10/13/2020 | HERON THERAPEUTICS, INC. /DE/ | HRTX | Grant | Restricted Stock Units | 58.3k | $0.00 | $0 | | 10/13/2020 |
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