| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 09/19/2022 | Trevi Therapeutics, Inc. | TRVI | Grant | Performance Stock Options (right to buy) | 32k | $3.21 | $102.7k | | 09/19/2022 |
| 06/29/2022 | Trevi Therapeutics, Inc. | TRVI | Grant | Performance Stock Options (right to buy) | 128k | $3.21 | $410.9k | | 06/29/2022 |
| 06/08/2022 | RHYTHM PHARMACEUTICALS, INC. | RYTM | Grant | Stock Option (right to buy) | 20k | $4.15 | $83k | | 06/08/2022 |
| 02/14/2022 | Trevi Therapeutics, Inc. | TRVI | Grant | Stock Option (right to buy) | 275k | $0.51 | $139.5k | | 02/14/2022 |
| 02/14/2022 | Trevi Therapeutics, Inc. | TRVI | Grant | Stock Option (right to buy) | 275k | $0.51 | $139.5k | | 02/14/2022 |
| 06/09/2021 | RHYTHM PHARMACEUTICALS, INC. | RYTM | Grant | Stock Option (right to buy) | 15k | $18.99 | $284.8k | | 06/09/2021 |
| 02/17/2021 | Trevi Therapeutics, Inc. | TRVI | Grant | Stock Option (right to buy) | 160k | $3.21 | $513.6k | | 02/17/2021 |
| 06/17/2020 | RHYTHM PHARMACEUTICALS, INC. | RYTM | Grant | Stock Option (right to buy) | 18.5k | $21.37 | $395.3k | | 06/17/2020 |
| 02/13/2020 | Trevi Therapeutics, Inc. | TRVI | Grant | Stock Option (right to buy) | 200k | $5.50 | $1.1M | | 02/13/2020 |
| 06/19/2019 | RHYTHM PHARMACEUTICALS, INC. | RYTM | Grant | Stock Option (right to buy) | 30k | $22.93 | $687.9k | | 06/19/2019 |
| 06/03/2019 | Trevi Therapeutics, Inc. | TRVI | Grant | Stock Option (right to buy) | 310k | $10.12 | $3.1M | | 06/03/2019 |
| 05/09/2019 | Trevi Therapeutics, Inc. | TRVI | Conversion | Series C Preferred Stock | 23.9k | $0.00 | $0 | | 05/09/2019 |
| 05/09/2019 | Trevi Therapeutics, Inc. | TRVI | Conversion | Series A Preferred Stock | 109k | $0.00 | $0 | | 05/09/2019 |
| 05/09/2019 | Trevi Therapeutics, Inc. | TRVI | Conversion | Common Stock | 18.3k | $0.00 | $0 | | 05/09/2019 |
| 05/09/2019 | Trevi Therapeutics, Inc. | TRVI | Purchase | Common Stock | 11.2k | $10.00 | $112.5k | | 05/09/2019 |
| 08/14/2018 | JUNIPER PHARMACEUTICALS INC | JNP | Disposition | Common Stock | 15k | $11.50 | $172.5k | | 08/14/2018 |
| 09/07/2017 | JUNIPER PHARMACEUTICALS INC | JNP | Grant | Common Stock, par value $0.01 | 15k | $0.00 | $0 | | 09/07/2017 |
| 03/05/2010 | PENWEST PHARMACEUTICALS CO | PPCO | Grant | Stock Option Right-to-buy | 140k | $3.04 | $425.6k | | 03/05/2010 |
| 11/11/2009 | PENWEST PHARMACEUTICALS CO | PPCO | Purchase | Common Stock | 7.5k | $2.14 | $16k | | 11/11/2009 |