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FIRST TRUST ADVISORS LP
> CRSP
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | CRISPR Therapeutics AG | CRSP | 96,398 | 96,398 | 5,411,783,000 | 5,411,783,000 | $56,139.99 |
| 03/31/2023 | CRISPR Therapeutics AG | CRSP | 0 | -61,545 | 0 | -4,022,000 | |
| 09/30/2022 | CRISPR Therapeutics AG | CRSP | 61,545 | 52,930 | 4,022,000 | 3,498,000 | $65.35 |
| 06/30/2022 | CRISPR Therapeutics AG | CRSP | 8,615 | 232 | 524,000 | -2,000 | $60.82 |
| 03/31/2022 | CRISPR Therapeutics AG | CRSP | 8,383 | 1,556 | 526,000 | 9,000 | $62.75 |
| 12/31/2021 | CRISPR Therapeutics AG | CRSP | 6,827 | -35,470 | 517,000 | -4,217,000 | $75.73 |
| 09/30/2021 | CRISPR Therapeutics AG | CRSP | 42,297 | 42,297 | 4,734,000 | 4,734,000 | $111.92 |
| 06/30/2021 | CRISPR Therapeutics AG | CRSP | 0 | -30,979 | 0 | -3,775,000 | |
| 03/31/2021 | CRISPR Therapeutics AG | CRSP | 30,979 | -34,023 | 3,775,000 | -6,177,000 | $121.86 |
| 12/31/2020 | CRISPR Therapeutics AG | CRSP | 65,002 | -1,309 | 9,952,000 | 4,406,000 | $153.10 |
| 09/30/2020 | CRISPR Therapeutics AG | CRSP | 66,311 | -3,098 | 5,546,000 | 445,000 | $83.64 |
| 06/30/2020 | CRISPR Therapeutics AG | CRSP | 69,409 | -21,724 | 5,101,000 | 1,236,000 | $73.49 |
| 03/31/2020 | CRISPR Therapeutics AG | CRSP | 91,133 | 91,133 | 3,865,000 | 3,865,000 | $42.41 |
| 12/31/2019 | CRISPR Therapeutics AG | CRSP | 0 | -24,085 | 0 | -987,000 | |
| 09/30/2019 | CRISPR Therapeutics AG | CRSP | 24,085 | 24,085 | 987,000 | 987,000 | $40.98 |
| 06/30/2019 | CRISPR Therapeutics AG | CRSP | 0 | -24,892 | 0 | -889,000 | |
| 03/31/2019 | CRISPR Therapeutics AG | CRSP | 24,892 | -8,977 | 889,000 | -79,000 | $35.71 |
| 12/31/2018 | CRISPR Therapeutics AG | CRSP | 33,869 | -59,478 | 968,000 | -3,172,000 | $28.58 |
| 09/30/2018 | CRISPR Therapeutics AG | CRSP | 93,347 | 8,295 | 4,140,000 | -858,000 | $44.35 |
| 06/30/2018 | CRISPR Therapeutics AG | CRSP | 85,052 | 85,052 | 4,998,000 | 4,998,000 | $58.76 |
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