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MARSHALL WACE, LLP
> BIIB
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | BIOGEN INC. | BIIB | 5,055 | -1,239,095 | 1,439,917,000 | -343,090,101,000 | $284,850.05 |
| 12/31/2022 | BIOGEN INC. | BIIB | 1,244,150 | 1,093,576 | 344,530,018,000 | 344,489,814,000 | $276,920.00 |
| 09/30/2022 | BIOGEN INC. | BIIB | 150,574 | 66,866 | 40,204,000 | 23,134,000 | $267.00 |
| 06/30/2022 | BIOGEN INC. | BIIB | 83,708 | -34,551 | 17,070,000 | -7,836,000 | $203.92 |
| 03/31/2022 | BIOGEN INC. | BIIB | 118,259 | 90,805 | 24,906,000 | 18,319,000 | $210.61 |
| 12/31/2021 | BIOGEN INC. | BIIB | 27,454 | 16,032 | 6,587,000 | 3,355,000 | $239.93 |
| 09/30/2021 | BIOGEN INC. | BIIB | 11,422 | -639,898 | 3,232,000 | -222,302,000 | $282.96 |
| 06/30/2021 | BIOGEN INC. | BIIB | 651,320 | 488,764 | 225,534,000 | 180,060,000 | $346.27 |
| 03/31/2021 | BIOGEN INC. | BIIB | 162,556 | -357,297 | 45,474,000 | -81,818,000 | $279.74 |
| 12/31/2020 | BIOGEN INC. | BIIB | 519,853 | 403,268 | 127,292,000 | 94,219,000 | $244.86 |
| 09/30/2020 | BIOGEN INC. | BIIB | 116,585 | 69,220 | 33,073,000 | 20,400,000 | $283.68 |
| 06/30/2020 | BIOGEN INC. | BIIB | 47,365 | -16,987 | 12,673,000 | -7,687,000 | $267.56 |
| 03/31/2020 | BIOGEN INC. | BIIB | 64,352 | 4,630 | 20,360,000 | 2,639,000 | $316.38 |
| 12/31/2019 | BIOGEN INC. | BIIB | 59,722 | 47,816 | 17,721,000 | 14,949,000 | $296.72 |
| 09/30/2019 | BIOGEN INC. | BIIB | 11,906 | 0 | 2,772,000 | -12,000 | $232.82 |
| 06/30/2019 | BIOGEN INC. | BIIB | 11,906 | 0 | 2,784,000 | -30,000 | $233.83 |
| 03/31/2019 | BIOGEN INC. | BIIB | 11,906 | 485 | 2,814,000 | -623,000 | $236.35 |
| 12/31/2018 | BIOGEN INC. | BIIB | 11,421 | -714 | 3,437,000 | -850,000 | $300.94 |
| 09/30/2018 | BIOGEN INC. | BIIB | 12,135 | 12,135 | 4,287,000 | 4,287,000 | $353.28 |
| 03/31/2018 | BIOGEN INC. | BIIB | 0 | -20,356 | 0 | -6,485,000 | |
| 12/31/2017 | BIOGEN INC. | BIIB | 20,356 | 11,946 | 6,485,000 | 3,853,000 | $318.58 |
| 09/30/2017 | BIOGEN INC. | BIIB | 8,410 | 3,632 | 2,632,000 | 1,337,000 | $312.96 |
| 06/30/2017 | BIOGEN INC. | BIIB | 4,778 | 1,420 | 1,295,000 | 378,000 | $271.03 |
| 03/31/2017 | BIOGEN INC. | BIIB | 3,358 | -85,489 | 917,000 | -24,278,000 | $273.08 |
| 12/31/2016 | BIOGEN INC. | BIIB | 88,847 | 37,313 | 25,195,000 | 9,063,000 | $283.58 |
| 09/30/2016 | BIOGEN INC. | BIIB | 51,534 | -140,007 | 16,132,000 | -30,186,000 | $313.04 |
| 06/30/2016 | BIOGEN INC. | BIIB | 191,541 | 179,419 | 46,318,000 | 43,162,000 | $241.82 |
| 03/31/2016 | BIOGEN INC. | BIIB | 12,122 | 12,122 | 3,156,000 | 3,156,000 | $260.35 |
| 12/31/2015 | BIOGEN INC. | BIIB | 201,721 | 201,721 | 61,797,000 | 61,797,000 | $306.35 |
| 09/30/2015 | BIOGEN INC. | BIIB | 12,365 | 12,365 | 3,609,000 | 3,609,000 | $291.87 |
| 06/30/2015 | BIOGEN INC. | BIIB | 123,859 | 123,859 | 50,031,000 | 50,031,000 | $403.94 |
| 03/31/2015 | BIOGEN INC. | BIIB | 76,611 | 76,611 | 32,349,000 | 32,349,000 | $422.25 |
| 12/31/2014 | BIOGEN INC. | BIIB | 133,866 | 133,866 | 45,441,000 | 45,441,000 | $339.45 |
| 09/30/2014 | BIOGEN INC. | BIIB | 12,932 | 12,932 | 4,278,000 | 4,278,000 | $330.81 |
| 06/30/2008 | BIOGEN INC. | BIIB | 0 | -106,770 | 0 | -6,587,000 | |
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