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TWO SIGMA INVESTMENTS, LP
> TMO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | THERMO FISHER SCIENTIFIC INC. | TMO | 419,834 | 177,479 | 219,048,390,000 | 79,362,239,000 | $521,750.00 |
| 03/31/2023 | THERMO FISHER SCIENTIFIC INC. | TMO | 242,355 | 241,155 | 139,686,151,000 | 139,025,323,000 | $576,370.00 |
| 12/31/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 1,200 | -82,130 | 660,828,000 | 615,556,000 | $550,690.00 |
| 06/30/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 83,330 | 83,330 | 45,272,000 | 45,272,000 | $543.29 |
| 03/31/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 0 | -339,085 | 0 | -226,251,000 | |
| 12/31/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 339,085 | 339,085 | 226,251,000 | 226,251,000 | $667.24 |
| 09/30/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 0 | -34,045 | 0 | -17,175,000 | |
| 06/30/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 34,045 | 34,045 | 17,175,000 | 17,175,000 | $504.48 |
| 03/31/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 0 | -21,772 | 0 | -4,872,000 | |
| 12/31/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 21,772 | 21,772 | 4,872,000 | 4,872,000 | $223.77 |
| 09/30/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 0 | -5,511 | 0 | -1,142,000 | |
| 06/30/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,511 | -61,030 | 1,142,000 | -12,596,000 | $207.22 |
| 03/31/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 66,541 | 66,541 | 13,738,000 | 13,738,000 | $206.46 |
| 12/31/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 0 | -58,494 | 0 | -11,067,000 | |
| 09/30/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 58,494 | 47,465 | 11,067,000 | 9,143,000 | $189.20 |
| 06/30/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 11,029 | -227,760 | 1,924,000 | -34,754,000 | $174.45 |
| 03/31/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 238,789 | -343,159 | 36,678,000 | -45,435,000 | $153.60 |
| 12/31/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 581,948 | 579,201 | 82,113,000 | 81,676,000 | $141.10 |
| 09/30/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 2,747 | -3,220 | 437,000 | -445,000 | $159.08 |
| 06/30/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,967 | 5,967 | 882,000 | 882,000 | $147.81 |
| 03/31/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 0 | -110,981 | 0 | -14,401,000 | |
| 12/31/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 0 | -110,981 | 0 | -14,401,000 | |
| 09/30/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 0 | -110,981 | 0 | -14,401,000 | |
| 06/30/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 110,981 | 64,605 | 14,401,000 | 10,476,000 | $129.76 |
| 03/31/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 290,703 | 244,327 | 39,053,000 | 35,128,000 | $134.34 |
| 12/31/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 202,325 | 155,949 | 25,349,000 | 21,424,000 | $125.29 |
| 09/30/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 412,554 | 366,178 | 50,208,000 | 46,283,000 | $121.70 |
| 06/30/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 202,192 | 155,816 | 23,859,000 | 19,934,000 | $118.00 |
| 03/31/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 244,657 | 198,281 | 29,418,000 | 25,493,000 | $120.24 |
| 12/31/2013 | THERMO FISHER SCIENTIFIC INC. | TMO | 0 | -2,404 | 0 | -222,000 | |
| 09/30/2013 | THERMO FISHER SCIENTIFIC INC. | TMO | 2,404 | -43,972 | 222,000 | -3,703,000 | $92.35 |
| 06/30/2013 | THERMO FISHER SCIENTIFIC INC. | TMO | 46,376 | 33,400 | 3,925,000 | 3,097,000 | $84.63 |
| 03/31/2013 | THERMO FISHER SCIENTIFIC INC. | TMO | 397,486 | 384,510 | 30,403,000 | 29,575,000 | $76.49 |
| 12/31/2012 | THERMO FISHER SCIENTIFIC INC. | TMO | 12,976 | 12,976 | 828,000 | 828,000 | $63.81 |
| 09/30/2012 | THERMO FISHER SCIENTIFIC INC. | TMO | 0 | -535,408 | 0 | -27,793,000 | |
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