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ETF MANAGERS GROUP, LLC
> OPK
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2022 | OPKO HEALTH, INC. | OPK | 192,641 | -35,160 | 240,801,000 | 240,370,000 | $1,250.00 |
| 09/30/2022 | OPKO HEALTH, INC. | OPK | 227,801 | 12,506 | 431,000 | -127,000 | $1.89 |
| 06/30/2022 | OPKO HEALTH, INC. | OPK | 215,295 | 8,623 | 558,000 | -174,000 | $2.59 |
| 03/31/2022 | OPKO HEALTH, INC. | OPK | 206,672 | -93,069 | 732,000 | -719,000 | $3.54 |
| 12/31/2021 | OPKO HEALTH, INC. | OPK | 299,741 | 51,025 | 1,451,000 | 546,000 | $4.84 |
| 09/30/2021 | OPKO HEALTH, INC. | OPK | 248,716 | 51,060 | 905,000 | 99,000 | $3.64 |
| 06/30/2021 | OPKO HEALTH, INC. | OPK | 197,656 | -7,573 | 806,000 | -60,000 | $4.08 |
| 03/31/2021 | OPKO HEALTH, INC. | OPK | 205,229 | -120,654 | 866,000 | -451,000 | $4.22 |
| 12/31/2020 | OPKO HEALTH, INC. | OPK | 325,883 | -49,695 | 1,317,000 | 29,000 | $4.04 |
| 09/30/2020 | OPKO HEALTH, INC. | OPK | 375,578 | 202,553 | 1,288,000 | 778,000 | $3.43 |
| 06/30/2020 | OPKO HEALTH, INC. | OPK | 173,025 | 173,025 | 510,000 | 510,000 | $2.95 |
| 12/31/2018 | OPKO HEALTH, INC. | OPK | 0 | -291,660 | 0 | -1,065,000 | |
| 09/30/2018 | OPKO HEALTH, INC. | OPK | 291,660 | 291,660 | 1,065,000 | 1,065,000 | $3.65 |
| 06/30/2018 | OPKO HEALTH, INC. | OPK | 0 | -195,663 | 0 | -604,000 | |
| 03/31/2018 | OPKO HEALTH, INC. | OPK | 195,663 | 195,663 | 604,000 | 604,000 | $3.09 |
| 09/30/2017 | OPKO HEALTH, INC. | OPK | 0 | -104,376 | 0 | -702,000 | |
| 06/30/2017 | OPKO HEALTH, INC. | OPK | 104,376 | 104,376 | 702,000 | 702,000 | $6.73 |
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