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JANUS HENDERSON GROUP PLC
> XENE
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Xenon Pharmaceuticals Inc. | XENE | 327,344 | 35,558 | 12,606,017,000 | 1,111,108,000 | $38,510.00 |
| 12/31/2022 | Xenon Pharmaceuticals Inc. | XENE | 291,786 | 57,952 | 11,494,909,000 | 11,486,478,000 | $39,395.00 |
| 09/30/2022 | Xenon Pharmaceuticals Inc. | XENE | 233,834 | -42,840 | 8,431,000 | 20,000 | $36.06 |
| 06/30/2022 | Xenon Pharmaceuticals Inc. | XENE | 276,674 | 266,393 | 8,411,000 | 8,096,000 | $30.40 |
| 03/31/2022 | Xenon Pharmaceuticals Inc. | XENE | 10,281 | 10,281 | 315,000 | 315,000 | $30.64 |
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