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LADENBURG THALMANN FINANCIAL SERVICES INC.
> MDCO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 09/30/2019 | MEDICINES CO /DE | MDCO | 1,048 | -1,478 | 52,000 | -40,000 | $49.62 |
| 06/30/2019 | MEDICINES CO /DE | MDCO | 2,526 | 381 | 92,000 | 32,000 | $36.42 |
| 03/31/2019 | MEDICINES CO /DE | MDCO | 2,145 | 146 | 60,000 | 22,000 | $27.97 |
| 12/31/2018 | MEDICINES CO /DE | MDCO | 1,999 | -385 | 38,000 | -33,000 | $19.01 |
| 09/30/2018 | MEDICINES CO /DE | MDCO | 2,384 | -131 | 71,000 | -12,000 | $29.78 |
| 06/30/2018 | MEDICINES CO /DE | MDCO | 2,515 | 102 | 83,000 | 17,000 | $33.00 |
| 12/31/2017 | MEDICINES CO /DE | MDCO | 2,413 | 32 | 66,000 | -23,000 | $27.35 |
| 09/30/2017 | MEDICINES CO /DE | MDCO | 2,381 | -162 | 89,000 | -8,000 | $37.38 |
| 06/30/2017 | MEDICINES CO /DE | MDCO | 2,543 | 1,143 | 97,000 | 28,000 | $38.14 |
| 03/31/2017 | MEDICINES CO /DE | MDCO | 1,400 | 180 | 69,000 | 27,000 | $49.29 |
| 12/31/2016 | MEDICINES CO /DE | MDCO | 1,220 | 466 | 42,000 | 13,000 | $34.43 |
| 09/30/2016 | MEDICINES CO /DE | MDCO | 754 | 0 | 29,000 | 3,000 | $38.46 |
| 06/30/2016 | MEDICINES CO /DE | MDCO | 754 | -46 | 26,000 | 1,000 | $34.48 |
| 03/31/2016 | MEDICINES CO /DE | MDCO | 800 | 269 | 25,000 | 8,000 | $31.25 |
| 12/31/2015 | MEDICINES CO /DE | MDCO | 720 | 189 | 27,000 | 10,000 | $37.50 |
| 09/30/2015 | MEDICINES CO /DE | MDCO | 747 | 216 | 28,000 | 11,000 | $37.48 |
| 06/30/2015 | MEDICINES CO /DE | MDCO | 782 | 251 | 22,000 | 5,000 | $28.13 |
| 03/31/2015 | MEDICINES CO /DE | MDCO | 448 | -83 | 13,000 | -4,000 | $29.02 |
| 12/31/2014 | MEDICINES CO /DE | MDCO | 748 | 217 | 20,000 | 3,000 | $26.74 |
| 09/30/2014 | MEDICINES CO /DE | MDCO | 448 | -83 | 10,000 | -7,000 | $22.32 |
| 06/30/2014 | MEDICINES CO /DE | MDCO | 472 | -59 | 14,000 | -3,000 | $29.66 |
| 03/31/2014 | MEDICINES CO /DE | MDCO | 628 | 97 | 18,000 | 1,000 | $28.66 |
| 12/31/2013 | MEDICINES CO /DE | MDCO | 552 | 21 | 21,000 | 4,000 | $38.04 |
| 09/30/2013 | MEDICINES CO /DE | MDCO | 572 | 41 | 19,000 | 2,000 | $33.22 |
| 06/30/2013 | MEDICINES CO /DE | MDCO | 531 | 17 | 17,000 | 4,000 | $32.02 |
| 03/31/2013 | MEDICINES CO /DE | MDCO | 796 | 282 | 27,000 | 14,000 | $33.92 |
| 12/31/2012 | MEDICINES CO /DE | MDCO | 514 | -31 | 13,000 | -1,000 | $25.29 |
| 09/30/2012 | MEDICINES CO /DE | MDCO | 545 | 321 | 14,000 | 8,000 | $25.69 |
| 06/30/2012 | MEDICINES CO /DE | MDCO | 224 | 0 | 6,000 | 1,000 | $26.79 |
| 03/31/2012 | MEDICINES CO /DE | MDCO | 224 | 224 | 5,000 | 5,000 | $22.32 |
| 12/31/2011 | MEDICINES CO /DE | MDCO | 224 | 224 | 5,000 | 5,000 | $22.32 |
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