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WELLS FARGO & COMPANY
> PPCO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2010 | PENWEST PHARMACEUTICALS CO | PPCO | 62,709 | 5,000 | 207,000 | 7,000 | $3.30 |
| 03/31/2010 | PENWEST PHARMACEUTICALS CO | PPCO | 57,709 | 53,744 | 200,000 | 189,000 | $3.47 |
| 12/31/2009 | PENWEST PHARMACEUTICALS CO | PPCO | 3,965 | 0 | 11,000 | 3,000 | $2.77 |
| 09/30/2009 | PENWEST PHARMACEUTICALS CO | PPCO | 3,965 | -4,000 | 8,000 | -14,000 | $2.02 |
| 06/30/2009 | PENWEST PHARMACEUTICALS CO | PPCO | 7,965 | -26,000 | 22,000 | -34,000 | $2.76 |
| 03/31/2009 | PENWEST PHARMACEUTICALS CO | PPCO | 33,965 | -2,600 | 56,000 | -2,000 | $1.65 |
| 12/31/2008 | PENWEST PHARMACEUTICALS CO | PPCO | 36,565 | 36,565 | 58,000 | 58,000 | $1.59 |
| 09/30/2008 | PENWEST PHARMACEUTICALS CO | PPCO | 0 | -38,576 | 0 | -104,000 | |
| 06/30/2008 | PENWEST PHARMACEUTICALS CO | PPCO | 38,576 | -3,000 | 104,000 | -4,000 | $2.70 |
| 03/31/2008 | PENWEST PHARMACEUTICALS CO | PPCO | 41,576 | 5,376 | 108,000 | -104,000 | $2.60 |
| 12/31/2007 | PENWEST PHARMACEUTICALS CO | PPCO | 36,200 | -58 | 212,000 | -188,000 | $5.86 |
| 09/30/2007 | PENWEST PHARMACEUTICALS CO | PPCO | 36,258 | 33 | 400,000 | -51,000 | $11.03 |
| 06/30/2007 | PENWEST PHARMACEUTICALS CO | PPCO | 36,225 | -669,575 | 451,000 | -6,664,000 | $12.45 |
| 03/31/2007 | PENWEST PHARMACEUTICALS CO | PPCO | 705,800 | -168,100 | 7,115,000 | -7,409,000 | $10.08 |
| 12/31/2006 | PENWEST PHARMACEUTICALS CO | PPCO | 873,900 | 873,000 | 14,524,000 | 14,509,000 | $16.62 |
| 09/30/2006 | PENWEST PHARMACEUTICALS CO | PPCO | 900 | -2,000 | 15,000 | -49,000 | $16.67 |
| 06/30/2006 | PENWEST PHARMACEUTICALS CO | PPCO | 2,900 | 179 | 64,000 | 6,000 | $22.07 |
| 03/31/2006 | PENWEST PHARMACEUTICALS CO | PPCO | 2,721 | 700 | 58,000 | 19,000 | $21.32 |
| 12/31/2005 | PENWEST PHARMACEUTICALS CO | PPCO | 2,021 | 21 | 39,000 | 4,000 | $19.30 |
| 09/30/2005 | PENWEST PHARMACEUTICALS CO | PPCO | 2,000 | -9,200 | 35,000 | -98,000 | $17.50 |
| 06/30/2005 | PENWEST PHARMACEUTICALS CO | PPCO | 11,200 | -700,300 | 133,000 | -8,662,000 | $11.88 |
| 03/31/2005 | PENWEST PHARMACEUTICALS CO | PPCO | 711,500 | -99,700 | 8,795,000 | -907,000 | $12.36 |
| 12/31/2004 | PENWEST PHARMACEUTICALS CO | PPCO | 811,200 | 800,000 | 9,702,000 | 9,575,000 | $11.96 |
| 09/30/2004 | PENWEST PHARMACEUTICALS CO | PPCO | 11,200 | 0 | 127,000 | -17,000 | $11.34 |
| 06/30/2004 | PENWEST PHARMACEUTICALS CO | PPCO | 11,200 | 0 | 144,000 | -20,000 | $12.86 |
| 03/31/2004 | PENWEST PHARMACEUTICALS CO | PPCO | 11,200 | -1,060 | 164,000 | -48,000 | $14.64 |
| 12/31/2003 | PENWEST PHARMACEUTICALS CO | PPCO | 12,260 | -404,800 | 212,000 | -8,863,000 | $17.29 |
| 09/30/2003 | PENWEST PHARMACEUTICALS CO | PPCO | 417,060 | 3,540 | 9,075,000 | -1,003,000 | $21.76 |
| 06/30/2003 | PENWEST PHARMACEUTICALS CO | PPCO | 413,520 | 344,887 | 10,078,000 | 8,981,000 | $24.37 |
| 03/31/2003 | PENWEST PHARMACEUTICALS CO | PPCO | 68,633 | -433,970 | 1,097,000 | -4,232,000 | $15.98 |
| 12/31/2002 | PENWEST PHARMACEUTICALS CO | PPCO | 502,603 | 92,090 | 5,329,000 | 1,924,000 | $10.60 |
| 09/30/2002 | PENWEST PHARMACEUTICALS CO | PPCO | 410,513 | 77,113 | 3,405,000 | -3,008,000 | $8.29 |
| 06/30/2002 | PENWEST PHARMACEUTICALS CO | PPCO | 333,400 | 17,230 | 6,413,000 | 300,000 | $19.24 |
| 03/31/2002 | PENWEST PHARMACEUTICALS CO | PPCO | 316,170 | -49,342 | 6,113,000 | -1,207,000 | $19.33 |
| 12/31/2001 | PENWEST PHARMACEUTICALS CO | PPCO | 365,512 | 32,405 | 7,320,000 | 1,581,000 | $20.03 |
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