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BlackRock Institutional Trust Company, N.A.
> CRXX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2010 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 181,821 | -342,431 | 264,000 | -3,400,000 | $1.45 |
| 12/31/2009 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 0 | -252,762 | 0 | -1,559,000 | |
| 09/30/2009 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 0 | -524,252 | 0 | -3,664,000 | |
| 06/30/2009 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 0 | -524,252 | 0 | -3,664,000 | |
| 03/31/2009 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 0 | -524,252 | 0 | -3,664,000 | |
| 12/31/2008 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 0 | -524,252 | 0 | -3,664,000 | |
| 09/30/2008 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 0 | -524,252 | 0 | -3,664,000 | |
| 06/30/2008 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 0 | -524,252 | 0 | -3,664,000 | |
| 03/31/2008 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 0 | -524,252 | 0 | -3,664,000 | |
| 12/31/2007 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 0 | -524,252 | 0 | -3,664,000 | |
| 09/30/2007 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 0 | -524,252 | 0 | -3,664,000 | |
| 06/30/2007 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 252,762 | -271,490 | 1,559,000 | -2,105,000 | $6.17 |
| 03/31/2007 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 524,252 | 524,252 | 3,664,000 | 3,664,000 | $6.99 |
| 12/31/2006 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 586,457 | 586,457 | 5,078,000 | 5,078,000 | $8.66 |
| 09/30/2006 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 451,226 | 451,226 | 2,810,000 | 2,810,000 | $6.23 |
| 06/30/2006 | EPIRUS Biopharmaceuticals, Inc. | CRXX | 478,360 | 478,360 | 4,203,000 | 4,203,000 | $8.79 |
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