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COLUMBIA WANGER ASSET MANAGEMENT LLC
> AGIO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 760,116 | -129,026 | 43,456,000 | -15,894,000 | $57.17 |
| 09/30/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 889,142 | 120,200 | 59,350,000 | 19,788,000 | $66.75 |
| 06/30/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 768,942 | 158,856 | 39,562,000 | 3,933,000 | $51.45 |
| 03/31/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 610,086 | -26,204 | 35,629,000 | 9,077,000 | $58.40 |
| 12/31/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 636,290 | 10,663 | 26,552,000 | -6,494,000 | $41.73 |
| 09/30/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 625,627 | 226,391 | 33,046,000 | 16,320,000 | $52.82 |
| 06/30/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 399,236 | -37,758 | 16,726,000 | -11,644,000 | $41.90 |
| 03/31/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 426,960 | -10,034 | 17,335,000 | -11,035,000 | $40.60 |
| 12/31/2015 | AGIOS PHARMACEUTICALS, INC. | AGIO | 436,994 | 436,994 | 28,370,000 | 28,370,000 | $64.92 |
| 09/30/2015 | AGIOS PHARMACEUTICALS, INC. | AGIO | 392,133 | 392,133 | 27,681,000 | 27,681,000 | $70.59 |
| 06/30/2015 | AGIOS PHARMACEUTICALS, INC. | AGIO | 476,604 | 476,604 | 52,970,000 | 52,970,000 | $111.14 |
| 03/31/2015 | AGIOS PHARMACEUTICALS, INC. | AGIO | 345,000 | 345,000 | 32,534,000 | 32,534,000 | $94.30 |
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