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MILLENNIUM MANAGEMENT LLC
> AVXL
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | ANAVEX LIFE SCIENCES CORP. | AVXL | 248,297 | -585,227 | 2,018,655,000 | 2,010,937,000 | $8,130.00 |
| 12/31/2022 | ANAVEX LIFE SCIENCES CORP. | AVXL | 833,524 | 630,156 | 7,718,000 | 5,619,000 | $9.26 |
| 09/30/2022 | ANAVEX LIFE SCIENCES CORP. | AVXL | 203,368 | -57,924 | 2,099,000 | -517,000 | $10.32 |
| 06/30/2022 | ANAVEX LIFE SCIENCES CORP. | AVXL | 261,292 | 261,292 | 2,616,000 | 2,616,000 | $10.01 |
| 03/31/2022 | ANAVEX LIFE SCIENCES CORP. | AVXL | 0 | -34,628 | 0 | -600,000 | |
| 12/31/2021 | ANAVEX LIFE SCIENCES CORP. | AVXL | 34,628 | -92,731 | 600,000 | -1,686,000 | $17.33 |
| 09/30/2021 | ANAVEX LIFE SCIENCES CORP. | AVXL | 127,359 | 28,391 | 2,286,000 | 24,000 | $17.95 |
| 06/30/2021 | ANAVEX LIFE SCIENCES CORP. | AVXL | 98,968 | 98,968 | 2,262,000 | 2,262,000 | $22.86 |
| 12/31/2020 | ANAVEX LIFE SCIENCES CORP. | AVXL | 0 | -10,359 | 0 | -51,000 | |
| 06/30/2020 | ANAVEX LIFE SCIENCES CORP. | AVXL | 10,359 | -99,283 | 51,000 | -294,000 | $4.92 |
| 03/31/2020 | ANAVEX LIFE SCIENCES CORP. | AVXL | 109,642 | 88,648 | 345,000 | 291,000 | $3.15 |
| 12/31/2019 | ANAVEX LIFE SCIENCES CORP. | AVXL | 20,994 | 20,994 | 54,000 | 54,000 | $2.57 |
| 09/30/2019 | ANAVEX LIFE SCIENCES CORP. | AVXL | 0 | -73,242 | 0 | -247,000 | |
| 06/30/2019 | ANAVEX LIFE SCIENCES CORP. | AVXL | 73,242 | 23,650 | 247,000 | 96,000 | $3.37 |
| 03/31/2019 | ANAVEX LIFE SCIENCES CORP. | AVXL | 49,592 | -51,188 | 151,000 | -6,000 | $3.04 |
| 12/31/2018 | ANAVEX LIFE SCIENCES CORP. | AVXL | 100,780 | -468,581 | 157,000 | -1,397,000 | $1.56 |
| 09/30/2018 | ANAVEX LIFE SCIENCES CORP. | AVXL | 569,361 | -98,345 | 1,554,000 | -195,000 | $2.73 |
| 06/30/2018 | ANAVEX LIFE SCIENCES CORP. | AVXL | 667,706 | 667,706 | 1,749,000 | 1,749,000 | $2.62 |
| 03/31/2018 | ANAVEX LIFE SCIENCES CORP. | AVXL | 0 | -44,895 | 0 | -145,000 | |
| 12/31/2017 | ANAVEX LIFE SCIENCES CORP. | AVXL | 44,895 | 21,895 | 145,000 | 50,000 | $3.23 |
| 09/30/2017 | ANAVEX LIFE SCIENCES CORP. | AVXL | 23,000 | -22,269 | 95,000 | -146,000 | $4.13 |
| 06/30/2017 | ANAVEX LIFE SCIENCES CORP. | AVXL | 45,269 | 45,269 | 241,000 | 241,000 | $5.32 |
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