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QVT Financial LP
> MBRX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2009 | METABASIS THERAPEUTICS INC | MBRX | 389,319 | 0 | 150,000 | -17,000 | $0.39 |
| 09/30/2009 | METABASIS THERAPEUTICS INC | MBRX | 389,319 | 0 | 167,000 | -51,000 | $0.43 |
| 06/30/2009 | METABASIS THERAPEUTICS INC | MBRX | 389,319 | 0 | 218,000 | -58,000 | $0.56 |
| 03/31/2009 | METABASIS THERAPEUTICS INC | MBRX | 389,319 | 0 | 276,000 | 151,000 | $0.71 |
| 12/31/2008 | METABASIS THERAPEUTICS INC | MBRX | 389,319 | -73,644 | 125,000 | -398,000 | $0.32 |
| 09/30/2008 | METABASIS THERAPEUTICS INC | MBRX | 462,963 | 462,963 | 523,000 | 523,000 | $1.13 |
| 06/30/2008 | METABASIS THERAPEUTICS INC | MBRX | 462,963 | 462,963 | 718,000 | 718,000 | $1.55 |
| 03/31/2008 | METABASIS THERAPEUTICS INC | MBRX | 462,963 | 462,963 | 954,000 | 954,000 | $2.06 |
| 12/31/2007 | METABASIS THERAPEUTICS INC | MBRX | 462,963 | 0 | 1,384,000 | 32,000 | $2.99 |
| 09/30/2007 | METABASIS THERAPEUTICS INC | MBRX | 462,963 | 0 | 1,352,000 | -1,889,000 | $2.92 |
| 06/30/2007 | METABASIS THERAPEUTICS INC | MBRX | 462,963 | 0 | 3,241,000 | -162,000 | $7.00 |
| 03/31/2007 | METABASIS THERAPEUTICS INC | MBRX | 462,963 | 0 | 3,403,000 | -78,000 | $7.35 |
| 12/31/2006 | METABASIS THERAPEUTICS INC | MBRX | 462,963 | 0 | 3,481,000 | 879,000 | $7.52 |
| 09/30/2006 | METABASIS THERAPEUTICS INC | MBRX | 462,963 | 0 | 2,602,000 | -930,000 | $5.62 |
| 06/30/2006 | METABASIS THERAPEUTICS INC | MBRX | 462,963 | 0 | 3,532,000 | -676,000 | $7.63 |
| 03/31/2006 | METABASIS THERAPEUTICS INC | MBRX | 462,963 | 462,963 | 4,208,000 | 4,208,000 | $9.09 |
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