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STATE STREET CORP
> HRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 2,331,238 | -255,694 | 2,704,236,000 | -3,763,094,000 | $1,160.00 |
| 12/31/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 2,586,932 | -6,251,774 | 6,467,330,000 | 6,430,031,000 | $2,500.00 |
| 09/30/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 8,838,706 | -7,490,090 | 37,299,000 | -8,258,000 | $4.22 |
| 06/30/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 16,328,796 | 3,405,427 | 45,557,000 | -28,365,000 | $2.79 |
| 03/31/2022 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 12,923,369 | 5,230,958 | 73,922,000 | 3,690,000 | $5.72 |
| 12/31/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 7,692,411 | 1,200,504 | 70,232,000 | 834,000 | $9.13 |
| 09/30/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 6,491,907 | 1,779,188 | 69,398,000 | -3,743,000 | $10.69 |
| 06/30/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 4,712,719 | 128,420 | 73,141,000 | -1,170,000 | $15.52 |
| 03/31/2021 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 4,584,299 | 602,495 | 74,311,000 | -9,964,000 | $16.21 |
| 12/31/2020 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 3,981,804 | -428,430 | 84,275,000 | 18,915,000 | $21.17 |
| 09/30/2020 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 4,410,234 | 569,776 | 65,360,000 | 8,867,000 | $14.82 |
| 06/30/2020 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 3,840,458 | 410,333 | 56,493,000 | 16,223,000 | $14.71 |
| 03/31/2020 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 3,430,125 | 54,068 | 40,270,000 | -39,067,000 | $11.74 |
| 12/31/2019 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 3,376,057 | 663,063 | 79,337,000 | 29,147,000 | $23.50 |
| 09/30/2019 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 2,712,994 | -1,349,319 | 50,190,000 | -25,328,000 | $18.50 |
| 06/30/2019 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 4,062,313 | 829,686 | 75,518,000 | -3,487,000 | $18.59 |
| 03/31/2019 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 3,232,627 | -253,365 | 79,005,000 | -11,422,000 | $24.44 |
| 12/31/2018 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 3,485,992 | 236,508 | 90,427,000 | -12,421,000 | $25.94 |
| 09/30/2018 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 3,249,484 | -217,402 | 102,848,000 | -31,840,000 | $31.65 |
| 06/30/2018 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 3,466,886 | 1,237,863 | 134,688,000 | 94,345,000 | $38.85 |
| 12/31/2017 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 2,229,023 | 308,202 | 40,343,000 | 9,320,000 | $18.10 |
| 09/30/2017 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,920,821 | 183,512 | 31,023,000 | 6,960,000 | $16.15 |
| 06/30/2017 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,737,309 | -50,369 | 24,063,000 | -2,759,000 | $13.85 |
| 03/31/2017 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,787,678 | 420,113 | 26,822,000 | 8,909,000 | $15.00 |
| 12/31/2016 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,367,565 | 270,022 | 17,913,000 | -1,002,000 | $13.10 |
| 09/30/2016 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,097,543 | 103,311 | 18,915,000 | 971,000 | $17.23 |
| 06/30/2016 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 994,232 | -214,340 | 17,944,000 | -5,003,000 | $18.05 |
| 03/31/2016 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,208,572 | 111,135 | 22,947,000 | -3,829,000 | $18.99 |
| 12/31/2015 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,424,311 | 326,874 | 38,027,000 | 11,251,000 | $26.70 |
| 09/30/2015 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,097,437 | -101,140 | 26,776,000 | -10,570,000 | $24.40 |
| 06/30/2015 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 1,198,577 | 900,822 | 37,346,000 | 33,011,000 | $31.16 |
| 03/31/2015 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 297,755 | 68,163 | 4,335,000 | 2,026,000 | $14.56 |
| 12/31/2014 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 229,592 | 15,227 | 2,309,000 | 528,000 | $10.06 |
| 09/30/2014 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 214,365 | 29,203 | 1,781,000 | -500,000 | $8.31 |
| 06/30/2014 | HERON THERAPEUTICS, INC. /DE/ | HRTX | 185,162 | 172,762 | 2,281,000 | 2,108,000 | $12.32 |
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