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SIGNET FINANCIAL MANAGEMENT, LLC
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 8,030 | 105 | 2,825,837,000 | 537,255,000 | $351,909.96 |
| 12/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 7,925 | 106 | 2,288,582,000 | 2,286,318,000 | $288,780.06 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 7,819 | 184 | 2,264,000 | 113,000 | $289.55 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 7,635 | 7,635 | 2,151,000 | 2,151,000 | $281.73 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -201 | 0 | -44,000 | |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 201 | 201 | 44,000 | 44,000 | $218.91 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -903 | 0 | -174,000 | |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 903 | 59 | 174,000 | 30,000 | $192.69 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 844 | 0 | 144,000 | 6,000 | $170.62 |
| 03/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 844 | 844 | 138,000 | 138,000 | $163.51 |
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