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ORBIMED ADVISORS LLC
> MREO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | MIRENCO INC | MREO | 0 | -7,747,891 | 0 | -5,476,984,000 | |
| 03/31/2023 | MIRENCO INC | MREO | 7,747,891 | -2,857,631 | 5,476,984,000 | -2,477,158,000 | $706.90 |
| 12/31/2022 | MIRENCO INC | MREO | 10,605,522 | 0 | 7,954,142,000 | 7,945,010,000 | $750.00 |
| 09/30/2022 | MIRENCO INC | MREO | 10,605,522 | 894,100 | 9,132,000 | -1,745,000 | $0.86 |
| 06/30/2022 | MIRENCO INC | MREO | 9,711,422 | -7,553,342 | 10,877,000 | -8,459,000 | $1.12 |
| 03/31/2022 | MIRENCO INC | MREO | 17,264,764 | 0 | 19,336,000 | -8,288,000 | $1.12 |
| 12/31/2021 | MIRENCO INC | MREO | 17,264,764 | 0 | 27,624,000 | -27,106,000 | $1.60 |
| 06/30/2021 | MIRENCO INC | MREO | 17,264,764 | 1 | 54,730,000 | -3,453,000 | $3.17 |
| 03/31/2021 | MIRENCO INC | MREO | 17,264,763 | 3,448,275 | 58,183,000 | 8,720,000 | $3.37 |
| 12/31/2020 | MIRENCO INC | MREO | 13,816,488 | 13,816,488 | 49,463,000 | 49,463,000 | $3.58 |
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