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Barrett Asset Management, LLC
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 14,222 | 39 | 3,711,000 | 596,000 | $260.93 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 14,183 | -14,427 | 3,115,000 | -2,075,000 | $219.63 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 28,610 | -872 | 5,190,000 | -754,000 | $181.41 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 29,482 | -10,199 | 5,944,000 | -2,583,000 | $201.61 |
| 03/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 39,681 | -2,964 | 8,527,000 | -3,078,000 | $214.89 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 34,261 | -8,384 | 8,097,000 | -3,508,000 | $236.33 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 42,645 | 16,863 | 11,605,000 | 4,120,000 | $272.13 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 25,782 | 14,467 | 7,485,000 | 4,793,000 | $290.32 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 11,315 | 11,170 | 2,692,000 | 2,667,000 | $237.91 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -145 | 0 | -25,000 | |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 145 | -45 | 25,000 | -10,000 | $172.41 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 190 | 0 | 35,000 | 0 | $184.21 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 190 | 0 | 35,000 | 4,000 | $184.21 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 190 | 190 | 31,000 | 31,000 | $163.16 |
| 06/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -165 | 0 | -13,000 | |
| 03/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 165 | 165 | 13,000 | 13,000 | $78.79 |
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