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TWO SIGMA ADVISERS, LP > IONS

DateNameTickerSharesChangeValueChangePrice
06/30/2023IONIS PHARMACEUTICALS INCIONS344,211-1,60014,122,977,0001,763,692,000$41,030.00
03/31/2023IONIS PHARMACEUTICALS INCIONS345,811-289,10012,359,285,000-11,621,303,000$35,740.00
12/31/2022IONIS PHARMACEUTICALS INCIONS634,911-22,60023,980,588,00023,951,506,000$37,770.00
09/30/2022IONIS PHARMACEUTICALS INCIONS657,511-48,30029,082,0002,953,000$44.23
06/30/2022IONIS PHARMACEUTICALS INCIONS705,81194,20026,129,0003,475,000$37.02
03/31/2022IONIS PHARMACEUTICALS INCIONS611,611114,20022,654,0007,518,000$37.04
12/31/2021IONIS PHARMACEUTICALS INCIONS497,41165,20015,136,000640,000$30.43
09/30/2021IONIS PHARMACEUTICALS INCIONS432,211-93,60014,496,000-6,479,000$33.54
06/30/2021IONIS PHARMACEUTICALS INCIONS525,811-188,60020,975,000-11,145,000$39.89
03/31/2021IONIS PHARMACEUTICALS INCIONS714,411-85,80032,120,000-13,124,000$44.96
12/31/2020IONIS PHARMACEUTICALS INCIONS800,211-289,90045,244,000-6,482,000$56.54
09/30/2020IONIS PHARMACEUTICALS INCIONS1,090,111-81,60051,726,000-17,358,000$47.45
06/30/2020IONIS PHARMACEUTICALS INCIONS1,171,711-15,50069,084,00012,953,000$58.96
03/31/2020IONIS PHARMACEUTICALS INCIONS1,187,211-179,60056,131,000-26,438,000$47.28
12/31/2019IONIS PHARMACEUTICALS INCIONS1,366,811-247,60082,569,000-14,150,000$60.41
09/30/2019IONIS PHARMACEUTICALS INCIONS1,614,411-20,30096,719,000-8,344,000$59.91
06/30/2019IONIS PHARMACEUTICALS INCIONS1,634,711827,800105,063,00039,566,000$64.27
03/31/2019IONIS PHARMACEUTICALS INCIONS806,911200,00065,497,00032,687,000$81.17
12/31/2018IONIS PHARMACEUTICALS INCIONS606,911298,70032,810,00016,912,000$54.06
09/30/2018IONIS PHARMACEUTICALS INCIONS308,211260,70015,898,00013,918,000$51.58
06/30/2018IONIS PHARMACEUTICALS INCIONS47,511-116,0001,980,000-5,228,000$41.67
03/31/2018IONIS PHARMACEUTICALS INCIONS163,51117,6007,208,000-131,000$44.08
12/31/2017IONIS PHARMACEUTICALS INCIONS145,911110,0007,339,0005,518,000$50.30
09/30/2017IONIS PHARMACEUTICALS INCIONS35,9116,8001,821,000340,000$50.71
06/30/2017IONIS PHARMACEUTICALS INCIONS29,11122,0001,481,0001,195,000$50.87
03/31/2017IONIS PHARMACEUTICALS INCIONS7,111-17,700286,000-901,000$40.22
12/31/2016IONIS PHARMACEUTICALS INCIONS24,811-46,4001,187,000-1,422,000$47.84
09/30/2016IONIS PHARMACEUTICALS INCIONS71,211-94,5002,609,000-1,250,000$36.64
06/30/2016IONIS PHARMACEUTICALS INCIONS165,711165,7113,859,0003,859,000$23.29
03/31/2016IONIS PHARMACEUTICALS INCIONS276,411276,41111,195,00011,195,000$40.50
12/31/2015IONIS PHARMACEUTICALS INCIONS395,539395,53924,496,00024,496,000$61.93
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