News + Filings Holdings
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TWO SIGMA ADVISERS, LP
> OPK
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | OPKO HEALTH, INC. | OPK | 1,439,197 | -358,100 | 3,123,057,000 | 499,003,000 | $2,170.00 |
| 03/31/2023 | OPKO HEALTH, INC. | OPK | 1,797,297 | -465,700 | 2,624,054,000 | -204,692,000 | $1,460.00 |
| 12/31/2022 | OPKO HEALTH, INC. | OPK | 2,262,997 | 140,600 | 2,828,746,000 | 2,824,735,000 | $1,250.00 |
| 09/30/2022 | OPKO HEALTH, INC. | OPK | 2,122,397 | 1,275,600 | 4,011,000 | 1,869,000 | $1.89 |
| 06/30/2022 | OPKO HEALTH, INC. | OPK | 846,797 | 504,597 | 2,142,000 | 965,000 | $2.53 |
| 03/31/2022 | OPKO HEALTH, INC. | OPK | 342,200 | 60,900 | 1,177,000 | -176,000 | $3.44 |
| 12/31/2021 | OPKO HEALTH, INC. | OPK | 281,300 | 261,000 | 1,353,000 | 1,279,000 | $4.81 |
| 09/30/2021 | OPKO HEALTH, INC. | OPK | 20,300 | -92,600 | 74,000 | -383,000 | $3.65 |
| 06/30/2021 | OPKO HEALTH, INC. | OPK | 112,900 | -76,000 | 457,000 | -353,000 | $4.05 |
| 03/31/2021 | OPKO HEALTH, INC. | OPK | 188,900 | 188,900 | 810,000 | 810,000 | $4.29 |
| 09/30/2020 | OPKO HEALTH, INC. | OPK | 0 | -908,632 | 0 | -3,098,000 | |
| 06/30/2020 | OPKO HEALTH, INC. | OPK | 908,632 | -319,700 | 3,098,000 | 1,452,000 | $3.41 |
| 03/31/2020 | OPKO HEALTH, INC. | OPK | 1,228,332 | 793,227 | 1,646,000 | 1,006,000 | $1.34 |
| 12/31/2019 | OPKO HEALTH, INC. | OPK | 435,105 | 435,105 | 640,000 | 640,000 | $1.47 |
| 09/30/2019 | OPKO HEALTH, INC. | OPK | 0 | -14,025 | 0 | -34,000 | |
| 06/30/2019 | OPKO HEALTH, INC. | OPK | 14,025 | 14,025 | 34,000 | 34,000 | $2.42 |
| 03/31/2019 | OPKO HEALTH, INC. | OPK | 0 | -16,400 | 0 | -49,000 | |
| 12/31/2018 | OPKO HEALTH, INC. | OPK | 16,400 | 16,400 | 49,000 | 49,000 | $2.99 |
| 12/31/2015 | OPKO HEALTH, INC. | OPK | 0 | -81,211 | 0 | -1,306,000 | |
| 09/30/2015 | OPKO HEALTH, INC. | OPK | 0 | -81,211 | 0 | -1,306,000 | |
| 06/30/2015 | OPKO HEALTH, INC. | OPK | 81,211 | 81,211 | 1,306,000 | 1,306,000 | $16.08 |
| 12/31/2014 | OPKO HEALTH, INC. | OPK | 0 | -28,600 | 0 | -243,000 | |
| 09/30/2014 | OPKO HEALTH, INC. | OPK | 28,600 | 28,600 | 243,000 | 243,000 | $8.50 |
| 03/31/2012 | OPKO HEALTH, INC. | OPK | 0 | -117,400 | 0 | -576,000 | |
| 12/31/2011 | OPKO HEALTH, INC. | OPK | 117,400 | 117,400 | 576,000 | 576,000 | $4.91 |
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