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Marshall Wace North America L.P.
> ZYME
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 09/30/2021 | Zymeworks BC Inc. | ZYME | 40,619 | 40,619 | 1,180,000 | 1,180,000 | $29.05 |
| 09/30/2020 | Zymeworks BC Inc. | ZYME | 0 | -290,524 | 0 | -10,478,000 | |
| 06/30/2020 | Zymeworks BC Inc. | ZYME | 290,524 | -8,300 | 10,478,000 | -121,000 | $36.07 |
| 03/31/2020 | Zymeworks BC Inc. | ZYME | 298,824 | -259,015 | 10,599,000 | -14,760,000 | $35.47 |
| 12/31/2019 | Zymeworks BC Inc. | ZYME | 557,839 | 399,993 | 25,359,000 | 21,444,000 | $45.46 |
| 09/30/2019 | Zymeworks BC Inc. | ZYME | 157,846 | 145,408 | 3,915,000 | 3,641,000 | $24.80 |
| 06/30/2019 | Zymeworks BC Inc. | ZYME | 12,438 | 12,438 | 274,000 | 274,000 | $22.03 |
| 09/30/2018 | Zymeworks BC Inc. | ZYME | 0 | -229,462 | 0 | -3,391,000 | |
| 06/30/2018 | Zymeworks BC Inc. | ZYME | 229,462 | 229,462 | 3,391,000 | 3,391,000 | $14.78 |
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