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ALLIANCEBERNSTEIN L.P.
> OPK
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | OPKO HEALTH, INC. | OPK | 619,469 | 0 | 1,344,248,000 | 439,823,000 | $2,170.00 |
| 03/31/2023 | OPKO HEALTH, INC. | OPK | 619,469 | 0 | 904,425,000 | 130,089,000 | $1,460.00 |
| 12/31/2022 | OPKO HEALTH, INC. | OPK | 619,469 | 13,469 | 774,336,000 | 773,191,000 | $1,250.00 |
| 09/30/2022 | OPKO HEALTH, INC. | OPK | 606,000 | 0 | 1,145,000 | -388,000 | $1.89 |
| 06/30/2022 | OPKO HEALTH, INC. | OPK | 606,000 | 6,600 | 1,533,000 | -529,000 | $2.53 |
| 03/31/2022 | OPKO HEALTH, INC. | OPK | 599,400 | 1,500 | 2,062,000 | -814,000 | $3.44 |
| 12/31/2021 | OPKO HEALTH, INC. | OPK | 597,900 | -300,000 | 2,876,000 | -401,000 | $4.81 |
| 09/30/2021 | OPKO HEALTH, INC. | OPK | 897,900 | 300,000 | 3,277,000 | 856,000 | $3.65 |
| 06/30/2021 | OPKO HEALTH, INC. | OPK | 597,900 | -13,700 | 2,421,000 | -203,000 | $4.05 |
| 03/31/2021 | OPKO HEALTH, INC. | OPK | 611,600 | 9,100 | 2,624,000 | 244,000 | $4.29 |
| 12/31/2020 | OPKO HEALTH, INC. | OPK | 602,500 | 4,600 | 2,380,000 | 174,000 | $3.95 |
| 09/30/2020 | OPKO HEALTH, INC. | OPK | 597,900 | 24,175 | 2,206,000 | 250,000 | $3.69 |
| 06/30/2020 | OPKO HEALTH, INC. | OPK | 573,725 | 52,300 | 1,956,000 | 1,257,000 | $3.41 |
| 03/31/2020 | OPKO HEALTH, INC. | OPK | 521,425 | 3,800 | 699,000 | -62,000 | $1.34 |
| 12/31/2019 | OPKO HEALTH, INC. | OPK | 517,625 | 11,600 | 761,000 | -297,000 | $1.47 |
| 09/30/2019 | OPKO HEALTH, INC. | OPK | 506,025 | 0 | 1,058,000 | -177,000 | $2.09 |
| 06/30/2019 | OPKO HEALTH, INC. | OPK | 506,025 | -413,240 | 1,235,000 | -1,164,000 | $2.44 |
| 03/31/2019 | OPKO HEALTH, INC. | OPK | 919,265 | 164,600 | 2,399,000 | 127,000 | $2.61 |
| 12/31/2018 | OPKO HEALTH, INC. | OPK | 754,665 | 285,930 | 2,272,000 | 650,000 | $3.01 |
| 09/30/2018 | OPKO HEALTH, INC. | OPK | 468,735 | 0 | 1,622,000 | -581,000 | $3.46 |
| 06/30/2018 | OPKO HEALTH, INC. | OPK | 468,735 | 293,651 | 2,203,000 | 1,648,000 | $4.70 |
| 03/31/2018 | OPKO HEALTH, INC. | OPK | 175,084 | 4,460 | 555,000 | -281,000 | $3.17 |
| 12/31/2017 | OPKO HEALTH, INC. | OPK | 170,624 | -47,670 | 836,000 | -661,000 | $4.90 |
| 09/30/2017 | OPKO HEALTH, INC. | OPK | 218,294 | 4,970 | 1,497,000 | 93,000 | $6.86 |
| 06/30/2017 | OPKO HEALTH, INC. | OPK | 213,324 | 33,400 | 1,404,000 | -35,000 | $6.58 |
| 03/31/2017 | OPKO HEALTH, INC. | OPK | 179,924 | -15,097 | 1,439,000 | -375,000 | $8.00 |
| 12/31/2016 | OPKO HEALTH, INC. | OPK | 195,021 | -1,911 | 1,814,000 | -272,000 | $9.30 |
| 09/30/2016 | OPKO HEALTH, INC. | OPK | 196,932 | 196,932 | 2,086,000 | 2,086,000 | $10.59 |
| 06/30/2016 | OPKO HEALTH, INC. | OPK | 255,882 | 255,882 | 2,390,000 | 2,390,000 | $9.34 |
| 03/31/2016 | OPKO HEALTH, INC. | OPK | 212,732 | 6,530 | 2,210,000 | 138,000 | $10.39 |
| 12/31/2015 | OPKO HEALTH, INC. | OPK | 206,202 | 206,202 | 2,072,000 | 2,072,000 | $10.05 |
| 09/30/2015 | OPKO HEALTH, INC. | OPK | 205,982 | 205,982 | 1,732,000 | 1,732,000 | $8.41 |
| 06/30/2015 | OPKO HEALTH, INC. | OPK | 153,600 | 153,600 | 2,470,000 | 2,470,000 | $16.08 |
| 03/31/2015 | OPKO HEALTH, INC. | OPK | 370,209 | -18,074 | 5,246,000 | 1,367,000 | $14.17 |
| 12/31/2014 | OPKO HEALTH, INC. | OPK | 388,283 | 388,283 | 3,879,000 | 3,879,000 | $9.99 |
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