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Marble Harbor Investment Counsel, LLC
> APNS
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 03/31/2010 | APPLIED NEUROSOLUTIONS INC | APNS | 10,000 | 0 | 7,000 | -4,000 | $0.70 |
| 12/31/2009 | APPLIED NEUROSOLUTIONS INC | APNS | 10,000 | 0 | 11,000 | 2,000 | $1.10 |
| 09/30/2009 | APPLIED NEUROSOLUTIONS INC | APNS | 10,000 | -290,000 | 9,000 | 2,000 | $0.90 |
| 06/30/2009 | APPLIED NEUROSOLUTIONS INC | APNS | 300,000 | 0 | 7,000 | 3,000 | $0.02 |
| 03/31/2009 | APPLIED NEUROSOLUTIONS INC | APNS | 300,000 | 0 | 4,000 | -3,000 | $0.01 |
| 12/31/2008 | APPLIED NEUROSOLUTIONS INC | APNS | 300,000 | 0 | 7,000 | -8,000 | $0.02 |
| 09/30/2008 | APPLIED NEUROSOLUTIONS INC | APNS | 300,000 | 0 | 15,000 | -1,000 | $0.05 |
| 06/30/2008 | APPLIED NEUROSOLUTIONS INC | APNS | 300,000 | 300,000 | 16,000 | 16,000 | $0.05 |
| 03/31/2008 | APPLIED NEUROSOLUTIONS INC | APNS | 300,000 | 0 | 28,000 | -5,000 | $0.09 |
| 12/31/2007 | APPLIED NEUROSOLUTIONS INC | APNS | 300,000 | 0 | 33,000 | -21,000 | $0.11 |
| 09/30/2007 | APPLIED NEUROSOLUTIONS INC | APNS | 300,000 | 0 | 54,000 | -6,000 | $0.18 |
| 06/30/2007 | APPLIED NEUROSOLUTIONS INC | APNS | 300,000 | 0 | 60,000 | -24,000 | $0.20 |
| 03/31/2007 | APPLIED NEUROSOLUTIONS INC | APNS | 300,000 | 150,000 | 84,000 | 36,000 | $0.28 |
| 12/31/2006 | APPLIED NEUROSOLUTIONS INC | APNS | 150,000 | 150,000 | 48,000 | 48,000 | $0.32 |
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