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HIGHLAND CAPITAL MANAGEMENT, LLC
> IONS
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | IONIS PHARMACEUTICALS INC | IONS | 0 | -37,598 | 0 | -1,343,753,000 | |
| 03/31/2023 | IONIS PHARMACEUTICALS INC | IONS | 37,598 | -2,712 | 1,343,753,000 | 1,342,230,000 | $35,740.01 |
| 12/31/2022 | IONIS PHARMACEUTICALS INC | IONS | 40,310 | 1,437 | 1,523,000 | -196,000 | $37.78 |
| 09/30/2022 | IONIS PHARMACEUTICALS INC | IONS | 38,873 | -286 | 1,719,000 | 269,000 | $44.22 |
| 06/30/2022 | IONIS PHARMACEUTICALS INC | IONS | 39,159 | 39,159 | 1,450,000 | 1,450,000 | $37.03 |
| 12/31/2019 | IONIS PHARMACEUTICALS INC | IONS | 0 | -3,440 | 0 | -206,000 | |
| 09/30/2019 | IONIS PHARMACEUTICALS INC | IONS | 3,440 | 240 | 206,000 | 0 | $59.88 |
| 06/30/2019 | IONIS PHARMACEUTICALS INC | IONS | 3,200 | 0 | 206,000 | -54,000 | $64.38 |
| 03/31/2019 | IONIS PHARMACEUTICALS INC | IONS | 3,200 | 3,200 | 260,000 | 260,000 | $81.25 |
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